Browsing by Author "Shaaban M.A.-E."

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    Synthesis, characterisation and biological screening of some 2-substituted benzimidazole derivatives as potential anticancer agents
    (Science Reviews 2000 Ltd, 2016) Shaaban M.A.-E.; Kamal A.M.; Teba H.E.-S.; Pharmaceutical Organic Chemistry Department; Faculty of Pharmacy; Cairo University; Cairo; 11561; Egypt; Pharmaceutical Organic Chemistry Department; Faculty of Pharmacy; October University for Modern Sciences and Arts (MSA); Cairo; Egypt
    Twenty two new polycyclic compounds containing a 2-substituted benzimidazole core were synthesised, characterised and evaluated in vitro against the three most widespread cancers. Seven compounds showed outstanding antitumor activity towards breast, lung or central nervous system cancer cell lines.