Browsing by Author "Ibrahem R.A."

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    Epidemiology of dermatophyte infections among school children in Menoufia Governorate, Egypt
    (Blackwell Publishing Ltd, 2018) Farag A.G.A.; Hammam M.A.; Ibrahem R.A.; Mahfouz R.Z.; Elnaidany N.F.; Qutubuddin M.; Tolba R.R.E.; Dermatology; Adrology and STDs Department; Faculty of Medicine; Menoufia University; Shebin El-Kom; Egypt; Department of Public Health and Community Medicine; Faculty of Medicine; Menoufia University; Shebin El-Kom; Egypt; Cleveland Clinic; Lerner College of Medicine; Case Western Reserve University; Cleveland; OH; United States; Clinical Pathology; Faculty of Medicine; Menoufia University; Shebin El-Kom; Egypt; Clinical Pharmacy; Faculty of Pharmacy; MSA University; October City; Egypt; Independent Researcher; Cleveland; OH; United States
    Most superficial mycotic infections of human skin are due to dermatophytes. Children are frequently affected due to different predisposing factors, particularly overcrowding in classrooms. This study aimed to estimate the prevalence of dermatophytes infections and their related risk factors among school children in Menoufia Governorate, Egypt. Six public primary and preparatory schools were randomly selected and their pupils (n=3464) were asked to complete a predesigned questionnaire covering both personal data and suspected risk factors for superficial dermatophyte infections. The children were also examined for dermatological diseases. Any suspected lesions were biopsied for mycological examination. The prevalence of clinically suspected dermatophytes infections was 1.41%, whereas the prevalence of culture confirmed cases was 0.98%. The most common clinical type was tinea capitis with a prevalence of 1.01%. Microsporum canis was the only isolated organism from the suspicious lesions with a 69.4% positivity rate. A higher prevalence was observed among boys, low socio-economic pupils and those with a family history of dermatophyte infections. Pet contact and sharing towels and caps among pupils were significant risk factors. Dermatophyte infection is still prevalent among basic school pupils. Fortunately, it is related to preventable risk factors. We recommend regular screening and use of educational health programmes for kids to control it. 2018 Blackwell Verlag GmbH
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    Tramadol (opioid) abuse is associated with a dose- and time-dependent poor sperm quality and hyperprolactinaemia in young men
    (Blackwell Publishing Ltd, 2018) Farag A.G.A.; Basha M.A.; Amin S.A.; Elnaidany N.F.; Elhelbawy N.G.; Mostafa M.M.T.; Khodier S.A.; Ibrahem R.A.; Mahfouz R.Z.; Dermatology; Andrology and STDs; Menoufia University; Shebin El Kom; Egypt; Forensic Medicine & Clinical Toxicology; Menoufia University; Shebin El Kom; Egypt; Faculty of Pharmacy; Clinical Pharmacy; MSA University; 6 October City; Egypt; Faculty of Medicine; Medical Biochemistry; Menoufia University; Shebin El Kom; Egypt; Faculty of Medicine; Clinical Pathology; Menoufia University; Shebin El Kom; Egypt; Faculty of Medicine; Public Health and Community Medicine; Menoufia University; Shebin El Kom; Egypt; Cleveland Clinic Lerner College of Medicine; Case Western Reserve University; Cleveland; OH; United States
    Tramadol, one of the most commonly abused drugs in Middle East, impacts spermatogenesis and disturbs reproductive hormones in animal studies. We aimed to investigate tramadol impact on sperm quality and on levels of testosterone, prolactin and gonadotropins, in tramadol abusers (n=30) to age-matched control (n=30). Abusers had significantly low percentages of sperm motility, normal forms and vitality compared with control (95% CI ?40.7 to ?19.3, ?13.5 to ?9.3 and ?31.9 to ?9.7 respectively). Hypoandrogenism (95% CI ?4.5 to ?2.8), hyperprolactinaemia (CI (95%) 4.9 to 9.4) and hypergonadotropinaemia (95% CI 2.9 to 7.2 for FSH and 2.0 to 7.8 for LH) were observed in tramadol abusers vs controls. Smokers (26 of 30), concurrently abusing other drugs (11 of 30) and asymptomatic leucocytospermic (15 of 30) patients subgroups significantly abused tramadol beyond 3years (p=.02, <.001, =.03 respectively) and in excess >450mg/day (p=.02, =.01, =.005 respectively). Progressive motility (a+b%) was significantly low in young men <25years old (p=.03) subgroup. Tramadol abuse is associated with poor sperm quality, hyperprolactinaemia and hypergonadotropic hypogonadism. We recommend semen analysis for tramadol long-intakes, question sperm donors and follow-up studies to prevent and reverse tramadol-induced testicular damage. � 2018 Blackwell Verlag GmbH