Browsing by Author "Gonaid, Mariam"

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    Crassulaceae (chemistry and pharmacology) - A review
    (ELSEVIER SCIENCE BV, 2018-12) Choucry, Mouchira; Gonaid, Mariam; Ezzat, Shahira M; Eid, Omneya
    Family Crassulaceae comprises approximately 1410 species which are commonly used for ornamental purposes. And nowadays showed many medicinal values. Recently, it has had been reported that several species of the family possess certain biological and pharmacological activities as: anti-oxidant, antihyperglycemic, antimicrobial, antiulcerogenic, cytotoxic/anti-cancer, anti-inflammatory, anti-nociceptive activity, hepatoprotective, analgesic, anti-arthritic, anti-malarial, antimutagenic, insecticidal, anti-thrombolytic, antihypertensive and myometrial activities. Earlier studies on different Crassulaceae plants have reported the isolation of flavonoids, sterols, ascorbic acid, trace elements, organic acids, hydrocarbons, triterpenoids, phenolic components and bufadienolides. This review contains an overview on the chemistry and pharmacological activities of Family Crassulaceae. (c) 2018 Future University. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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    Novel Cycloartan derivative with genetic and metabolic proৎiling oftwo Crassulaceae species
    (JK Welfare & Pharmascope Foundation, 2020-12) Eid, Omneya; Ezzat, Shahira M; Gonaid, Mariam; Choucry, Mouchira
    and C. ovata respectively. The unsaponifiable matter (USM) of n-hexane extract of C. tetragona and C. ovata revealed the presence of 32 hydrocarbons with the presence of n-tricontane as the major hydrocarbon in both species, in addition to seven steroidal components in both species. The investigation of fatty acid methyl ester (FAME) revealed the presence of 12 components in C. tetragona and 9 components in C. ovata, and a novel triterpene, namely, 28 Methyl-5α-cycloart12, 20, 24-trien-15β-Ol was isolated and identified from MeCl together with 5 known compounds.