Browsing by Author "Fokou, P.V.T"

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    Dioscorea plants: A genus rich in vital nutra-pharmaceuticals-A review
    (Iranian Journal of Pharmaceutical Research, 2019) Salehi, B; Sener, B; Kilic, M; Sharifi-Rad, J; Naz, R; Yousaf, Z; Mudau, F.N; Fokou, P.V.T; Ezzat, Shahira M; El Bishbishy, M.H; Taheri, Y; Lucariello, G; Durazzo, A; Lucarini, M; Suleria, H.A.R; Santini, A
    Dioscorea species, known as “Yams,” belong to family Dioscoreaceae. This genus consists of more than 600 species distributed from Africa, Asia, the Caribbean’s South America, and the South Pacific islands. Their organoleptic properties make them the most widely used carbohydrate food and dietary supplements. The underground and/or aerial tubers represent valuable sources of proteins, fats, and vitamins for millions of people in West Africa. This review gives a shot of secondary metabolites of Dioscorea plants, including steroids, clerodane diterpenes, quinones, cyanidins, phenolics, diarylheptanoids, and nitrogen-containing compounds. This review collected the evidence on biological properties of description Dioscorea, including in-vitro and in-vivo studies. Dioscorea species contain promising bioactive molecules i.e. diosgenin that support their different biological properties, including antioxidant, hypoglycaemic, hypolipidemic, anti-antimicrobial, inflammatory, antiproliferative, androgenic, estrogenic, and contraceptive drugs. Indeed, besides its nutrient values, Dioscorea is a potential source of bioactive substances of interest in the prevention/ treatment of several diseases, and thus represents a great challenge in developing countries. However, ethnomedicinal potential should be validated and further researches on pharmacological properties and phytochemical composition should be carried out. Particularly, doing some studies to convert the preclinical results to clinical efficacy should be guaranteed.
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    Rosmarinus plants: Key farm concepts towards food applications
    (John Wiley and Sons Ltd, 2020) Martins, N; Fokou, P.V.T; Salehi, B; Pignata, G; Nicola, S; Atanassova, M; Sharifi-Rad, M; Constantin, C; Kılıç, C.S; Sharopov, F; Mnayer, D; El Bishbishy, M.H; Ezzat, Shahira M; Sharifi-Rad, J
    Rosmarinus species are aromatic plants that mainly grow in the Mediterranean region. They are widely used in folk medicine, food, and flavor industries and represent a valuable source of biologically active compounds (e.g., terpenoids, flavonoids, and phenolic acids). The extraction of rosemary essential oil is being done using three main methods: carbon dioxide supercritical extraction, steam distillation, and hydrodistillation. Furthermore, interesting antioxidant, antibacterial, antifungal, antileishmanial, anthelmintic, anticancer, anti-inflammatory, antidepressant, and antiamnesic effects have also been broadly recognized for rosemary plant extracts. Thus the present review summarized data on economically important Rosmarinus officinalis species, including isolation, extraction techniques, chemical composition, pharmaceutical, and food applications. © 2020 John Wiley & Sons, Ltd.