Browsing by Author "Ezzeldin, Naglaa"

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COMPARATIVE EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF GLASS IONOMER RESTORATION INCORPORATED WITH DIFFERENT METAL OXIDES NANOPARTICLES ON ORAL STREPTOCOCCUS MUTANS
(EDJ, 2019-10) Ezzeldin, Naglaa; Elshishtawy, Hisham; El-Borady, Ola; Mohamed, Mona
Objective: The objective of this study is to compare and evaluate the antibacterial activity of modified conventional Glass ionomer restoration (GI) with zinc oxide (ZnO-NPs) and cerium oxide Nanoparticles (CeO2-NPs) on the oral Streptococcus mutans (SM). Materials and Methods: one hundred and five disc-shaped specimens were divided into seven groups; GI, GI incorporated with three, five and seven percent ZnO-NPs and CeO2-NPs. Antibacterial activity was assessed by counting of colony forming unit (CFU) of SM after direct contact test and 96 hours biofilm evaluation. Fourier transform infrared spectroscopy (FTIR) was used to illustrate interaction between different concentrations of Nanoparticles incorporated with GI. Results: Direct contact test showed a significant reduction of CFU of GI incorporated with seven percent ZnO-NPs in relation to GI (P value 0.007). Biofilm evaluation showed significant reduction of CFU of GI incorporated with three, five and seven percent ZnO-NPs and five and seven percent CeO2-NPs (P value 0.000). FTIR showed Peaks at 1405 and 1635 cm–1 related to symmetric and asymmetric vibrations of COO−, those peaks were broader and red shifted in GI incorporated with ZnO-NPs and CeO-NPs. Conclusion: Incorporation of conventional GI with ZnO-NPs and CeO2-NPs enhance its antibacterial activity against oral SM.
Diagnostic errors in Dentistry, opinions of egyptian dental teaching staf, a cross‑sectional study
(BioMed Central Ltd., 2022-12) El‑Wakeel, Naglaa; Ezzeldin, Naglaa
Background: Diagnostic errors is a known problem in healthcare practice. Data on diagnostic errors in the dental feld are extremely lacking. The objective of the study is to explore the perception of dental teaching staf about the prevalence of dental diagnostic errors in Egypt, identify the most commonly misdiagnosed dental conditions and point out the contributing factors and levels of patient harm. Methods: A cross-sectional questionnaire-based study was conducted on 151 dental teaching staf of Egyptian gov‑ ernmental and private universities. The questionnaire was distributed electronically via social media and messaging apps to dental staf members with at least fve years of clinical experience to assess their opinion regarding the study objectives. Results were collected and statistically analyzed. Results: 94.7% of participants believed that diagnostic errors represent an urgent problem, lecturers believed by 2.703 folds more than professors that diagnostic errors are an urgent problem The percentage of diagnostic errors was estimated to be <20% and 20–40% by more than 90% of participants. The most commonly misdiagnosed conditions were oral mucosal lesions (83.4%), followed by temporomandibular joint and periodontal conditions (58.9%) for each. More than half of the participants (60.9%) believe that medical education methodology is one of the factors that lead to dental diagnosis errors. For the impact of errors on patients, 53% of participants reported moderate impacts fol‑ lowed by minor impact (37.7%) while 4.6% reported no impact and the same percentage reported major impact. Conclusion: This study with statistically signifcant results reported that dental diagnostic errors are frequent and need to be approached. Oral mucosal lesions, periodontal and temporomandibular joint diseases represent areas that include the most commonly seen errors. Further, besides the lack of resources, the dental education system and lack of proper training are the main causes of this problem.
Evaluation of Surface Properties of Two Remineralizing Agents after Modification by Chitosan Nano Particles: An In vitro Study
(Wolters Kluwer Medknow Publications, 2023-12) Wahied, Dina Mohamed; Ezzeldin, Naglaa; Abdelnabi, Ali; Othman, Maha Sherif; Abd El Rahman, Mai Hesham
Background: Calcium phosphate‑based systems have been introduced as promising bio‑mimetic materials due to their close resemblance to the enamel. Chitosan and its derivatives have been an emerging biomaterial due to their additional antibacterial effect and promising re‑mineralizing ability. Aim: The aim of this study is to evaluate the effect of chitosan nanoparticles on the remineralization of the demineralized enamel surface after being added to nano‑hydroxyapatite and nano‑calcium phosphate materials. Setting and Design: This was in vitro study. Materials and Methods: Twenty specimens of extracted permanent molars were collected, and then immersed in demineralizing solution, then distributed into four groups according to the remineralizing material. Group 1: Treated with Nano‑beta‑tricalcium phosphate (Nβ‑TCP) gel, Group 2: Treated with Nβ‑TCP with chitosan gel, Group 3: Treated with Nanohydroxyapatite (NHA) gel, and Group 4: Treated with NHA with chitosan gel. The surface hardness of the teeth was measured at baseline, after demineralization, and after remineralization. The structural changes in each group were analyzed using the scanning electron microscopy. Statistical Analysis: Shapiro–Wilk’s test, one‑way ANOVA followed by Tukey’s post hoc test was used. Results: In all groups, there was a significant difference in mean Vickers hardness number (VHN) at different intervals, with the highest value found after treatment (301.64–395.65) VHN, followed by the baseline (236.97–276.15) VHN, while the lowest value was detected after demineralization (121.23–124.39) VHN. It was also indicated that baseline treatment, the Hardness percentage change (%) of the nano NHA + Chitosan group showed the highest significant value (55.10%), while the Nβ‑TCP group exhibited the lowest significant value (9.56%). Conclusions: It can be concluded that NHA and NΒ‑TCP modified by chitosan NPs as remineralizing agents of enamel surface hold promising results.