Browsing by Author "Ayob, Menar M"

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    Immunohistochemical expression of HER-2/neu receptors in gastric carcinoma
    (Medknow Publications, 07/01/2017) Ishaky, Elia A; El-Sharkawy, Sonia L; Ayob, Menar M; Sharaf, Hafiza A; Bakeer, Rofanda M
    Background/aim Gastric carcinoma is the fourth most commonly diagnosed cancer and the second most common cause of cancer-related death. It is associated with patient morbidity and mortality worldwide. Adenocarcinomas represent 90% of gastric carcinoma cases and are classified into intestinal and diffuse types. Human epidermal growth factor receptor 2 (HER-2)/neu overexpression is a predictor of poor prognosis. This study aimed to evaluate HER-2/neu expression in gastric carcinomas and to correlate its expression with clinicopathological parameters and other prognostic factors.