Browsing by Author "A Hammam, Mostafa"
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Item Role of chemokine ligand 22 in narrow-band ultraviolet B-induced pigmentation in vitiligo: an immunohistochemical study(Medknow Publications, 2019) G Antar Farag, Azza; A Hammam, Mostafa; R Al-Sharaky, Dalia; A Hassan, Reem; N ElShafey, Eman; A Ali, NehalChemokine ligand 22 (CCL22) is a heparin-binding immunomodulator protein that plays an important role in a variety of autoimmune diseases. Narrow-band ultraviolet B (NB-UVB) therapy was considered a cornerstone in the treatment of vitiligo. However, the mechanism of action of NB-UVB in vitiligo has not been completely elucidated. Objective To study the hypothesized role of CCL22 in vitiligo etiopathogenesis and to detect its possible role in NB-UVB-induced pigmentation in vitiligo through its lesional immunohistochemical evaluation in patients with vitiligo before and after ultraviolet B phototherapy.