dc.contributor.author |
Kamel, Noha A. |
|
dc.contributor.author |
El-tayeb, Wafaa N. |
|
dc.contributor.author |
El-Ansary, Mona R. |
|
dc.contributor.author |
Mansour, Mohamed T. |
|
dc.contributor.author |
Aboshanab, Khaled M. |
|
dc.date.accessioned |
2019-11-20T10:31:32Z |
|
dc.date.available |
2019-11-20T10:31:32Z |
|
dc.date.issued |
2018 |
|
dc.identifier.issn |
1932-6203 |
|
dc.identifier.other |
https://doi.org/10.1371/journal.pone.0202119 |
|
dc.identifier.uri |
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202119 |
|
dc.description |
Accession Number: WOS:000443071400037 |
en_US |
dc.description.abstract |
A total of 185 GNB were recovered from different clinical specimens, Escherichia (E.) coli (86; 46.48%), followed by Klebsiella spp. (71; 38.37%), Acinetobacter (A.) baumannii (7; 3.78%) and others including Pseudomonas spp., Enterobacter (Ent.) cloacae and Proteus spp. (21; 11.35%). It is a matter of concern that 116 out of 171 enterobacterial isolates (94.15%) showed resistance to three or more antimicrobial classes and were considered multidrug resistant. Additionally, the rate of carbapenem-resistance displayed a worrisome trend as 113 out of 171 enterobacterial isolates (66.08%) and 12 out of 14 non fermenting bacilli (85.71%) showed resistance pattern to at least one of the tested carbapenems. After performing a series of phenotypic tests for initial screening of potential carbapenemase producers, molecular characterization to the 29 extracted plasmids were subjected to PCR using 5 common carbapenemase primers). The results revealed that bla(OXA-48) was the most prevalent 17 (58.62%), followed by bla(NDM) 8(27.58%), then bla(VIM) 3 (10.3%) and bla(KPC) 2 (6.89%). |
en_US |
dc.description.sponsorship |
PUBLIC LIBRARY SCIENCE |
en_US |
dc.description.uri |
https://www.scimagojr.com/journalsearch.php?q=10600153309&tip=sid&clean=0 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
PUBLIC LIBRARY SCIENCE |
en_US |
dc.relation.ispartofseries |
PLOS ONE;Volume: 13 Issue: 8 |
|
dc.relation.uri |
https://cutt.ly/reZmHEV |
|
dc.subject |
University of BLOOD-STREAM INFECTIONS |
en_US |
dc.subject |
BLUE-CARBA TEST |
en_US |
dc.subject |
ACUTE-LEUKEMIA |
en_US |
dc.subject |
MULTIPLEX PCR |
en_US |
dc.title |
Phenotypic screening and molecular characterization of carbapenemase-producing Gram-negative bacilli recovered from febrile neutropenic pediatric cancer patients in Egypt |
en_US |
dc.type |
Article |
en_US |
dc.identifier.doi |
https://doi.org/10.1371/journal.pone.0202119 |
|
dc.Affiliation |
October University for modern sciences and Arts (MSA) |
|