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| dc.contributor.author | Ezzat, Shahira M | |
| dc.contributor.author | M Abdallah, Hossam | |
| dc.contributor.author | A Fawzy, Ghada | |
| dc.contributor.author | A El-Maraghy, Shohda | |
| dc.date.accessioned | 2019-11-04T06:41:43Z | |
| dc.date.available | 2019-11-04T06:41:43Z | |
| dc.date.issued | 2012 | |
| dc.identifier.citation | Aebi, H. (1974). Catalase. In H.U. Bergmeyer (Ed.), Methods in enzymatic analysis (Vol. 2). New York: Academic Press. Agarwal, M., Srivastava, V.K., Saxena, K.K. & Kumar, A. (2006). Hepatoprotective activity of Beta vulgaris against CCl4-induced hepatic injury in rats. Fitoterapia, 77, 91–93. Beaufay, H., Amar-Costesec, A., Ernest, F., Thines-Sempoux, D., Wibo, M., Robbi, M., & Berthet, J. (1974). Analytical study of microsomes and isolated subcellular membranes from rat liver. Journal of Cell Biology, 61, 188–200. Beutler, E., Duron, O., & Kelly, B.M. (1963). Improved method for the determination of blood glutathione. Journal of Laboratory Clinical Medicine, 61, 882–888. Buhl, S.N., & Jackson, K.Y. (1978). Optical conditions and comparisons of lactate dehydrogenase catalysis of the lactate to pyruvate and pyruvate to lactate reactions in human serum at 25, 30 and 37°C. Clinical Chemistry, 24, 828–831. Karber, G. (1931). Determination of LD50. Archives of Experimental Pathology and Pharmacology, 162, 480–488. Krawisz, J.E., Sharon, P., & Stenson, W.F. (1984). Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity: assessment of inflammation in rat and hamster models. Gastroenterology, 87, 1344–1350. Lowry, O.H., Rosebrough, N.J., Farr, A.L., & Randall, R.G. (1951). Protein measurement with Folin reagent. Journal of Biological Chemistry, 193, 265–275. Miranda, M.M., Espey, M.G., & Wink, D.A. (2001). A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide, 5, 62–71. Paglia, D.E., & Valentine, W.N. (1967). Studies on the quantitative and qualitative characterization of erythrocytes glutathione peroxidase. Journal of Laboratory Clinical Medicine, 70, 158–169. Reitman, S., & Frankel, S. (1957). A colorimetric method for the determination of serum glutamic oxaloacetic acid and glutamic pyruvic transaminases. American Journal of Clinical Pathology, 28, 56–63. Uchiyama, M., & Mihara, M. (1978). Determination of malondialdehyde precursor in tissue by thiobarbituric acid method. Analytical Biochemistry, 86, 271–278. Valeer, J.D. (2003). Liver tissue examination. Journal of Hepatology, 39, S43–S49. | en_US |
| dc.identifier.other | https://doi.org/ | |
| dc.identifier.uri | https://cutt.ly/KtwkrJd | |
| dc.description | MSA Google Scholar | |
| dc.description.abstract | An investigation of the aqueous ethanolic extract (AE) of the aerial parts of Torilis radiata Moench yielded two triterpenes (lupeol acetate 1 and α-amyrin 2), a sterol (spinasterol 3) from its n-hexane fraction (HF), a flavone (acacetin 4), a coumarin (scopoletin 5), a phenolic acid (ferulic acid 6) from the chloroform fraction (CF) and a flavone glycoside (luteolin-7- O-glucoside 7) from the n-butanol fraction (BF). The hepatoprotection of the AE and its fractions was assessed in terms of the reduction in histological damage, accompanied by restoration of the liver enzymes (alanine amino transferase (ALT), aspartate amino transferase (AST), lactate dehydrogenase (LDH)), a reduction in the inflammatory markers (tumour necrosis-α (TNF-α), nitric oxide (NO), N-acetyl-β-D-glucosaminidase (NAG) and myloperoxidase (MPO) in serum), and a restoration of the oxidant balance through decreasing the serum and hepatic malondialdehyde (MDA) levels, along with increasing the activity of hepatic catalase (CAT), glutathione peroxidase (GSHPx) and the non-enzymatic antioxidant glutathione (GSH). | en_US |
| dc.description.sponsorship | Taylor & Francis Group | en_US |
| dc.description.uri | https://www.scimagojr.com/journalsearch.php?q=24819&tip=sid&clean=0 | |
| dc.language.iso | en | en_US |
| dc.publisher | Taylor & Francis Group | en_US |
| dc.relation.ispartofseries | Natural product research;26:3 , 282-285 | |
| dc.subject | antioxidant | en_US |
| dc.subject | anti-inflammatory | en_US |
| dc.subject | hepatoprotective | en_US |
| dc.subject | Torilis radiata | en_US |
| dc.title | Hepatoprotective constituents of Torilis radiata Moench (Apiaceae) | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | https://doi.org/ | |
| dc.Affiliation | October University for modern sciences and Arts (MSA) |
