Antihyperglycemic and antihyperlipidemic effects of the methanol extracts of Cleome ramosissima Parl., Barleria bispinosa (Forssk.) Vahl. and Tribulus macropterus Boiss.

Ezzat, Shahira M; Abdel-Sattar, Essam; M. Harraz, Fathalla; A. Ghareib, Salah

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dc.contributor.author	Ezzat, Shahira M
dc.contributor.author	Abdel-Sattar, Essam
dc.contributor.author	M. Harraz, Fathalla
dc.contributor.author	A. Ghareib, Salah
dc.date.accessioned	2019-10-21T06:30:14Z
dc.date.available	2019-10-21T06:30:14Z
dc.date.issued	2014
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dc.identifier.issn	1110-0931
dc.identifier.other	https://doi.org/10.1016/j.bfopcu.2013.12.002
dc.identifier.uri	https://cutt.ly/PtwEzFr
dc.description	MSA Google Scholar
dc.description.abstract	The antihyperglycemic and antihyperlipidemic effects of the methanolic extracts of the aerial parts of Cleome ramosissima Parl. (Cleomaceae), Barleria bispinosa (Forssk.) Vahl. (Acanthaceae) and Tribulus macropterus Boiss. (Zygophyllaceae) were evaluated in streptozotocin (STZ) induced diabetic rats at a dose of 500 mg/kg bw. The reduction in fasting blood glucose level (BGL) was observed in the following order C. ramosissima, B. bispinosa and T. macropterus at the 4th week of administration. C. ramosissima and T. macropterus also showed significant increase in plasma insulin by 100.6% and 189.9%, respectively. The studied plant extracts induced an increase in both utilization and tolerance of glucose in diabetic rats. The hypolipidemic effect of C. ramosissima and T. macropterus was demonstrated by a significant reduction in plasma total cholesterol (TC) (42.6% and 37.2%, respectively) and low density lipoprotein cholesterol (LDL-C) (48.0% and 42.1%, respectively) and the increase of high density lipoprotein cholesterol (HDL-C) by 81.0% and 91.9%, respectively. B. bispinosa decreased the blood levels of LDL-C	en_US
dc.description.sponsorship	Faculty of Pharmacy, Cairo University	en_US
dc.description.uri	https://www.scimagojr.com/journalsearch.php?q=21100853576&tip=sid&clean=0
dc.language.iso	en	en_US
dc.publisher	Faculty of Pharmacy, Cairo University	en_US
dc.relation.ispartofseries	Bulletin of Faculty of Pharmacy, Cairo University;
dc.subject	University of Antidiabetic	en_US
dc.subject	Hypolipidemic	en_US
dc.title	Antihyperglycemic and antihyperlipidemic effects of the methanol extracts of Cleome ramosissima Parl., Barleria bispinosa (Forssk.) Vahl. and Tribulus macropterus Boiss.	en_US
dc.type	Article	en_US
dc.identifier.doi	https://doi.org/10.1016/j.bfopcu.2013.12.002
dc.Affiliation	October University for modern sciences and Arts (MSA)