Abstract:
Pharmaceuticals wastes and their ways of disposal are an alarming problem nowadays and it is
earning more awareness and realization from consumers and also professionals of healthcare.
The acceleration in pollution in the environment coupled with the increase of wastes entering the
eco-system has attracted the interest of researchers to focus on finding a way to remove these
wastes in the most proper manner. Phenolic waste compounds mainly found in water and soil
due to pollution from several industries such as petroleum, pesticides, plastic and pharmaceutical
industries. phenolic compounds are harmful to human health and causes many health problems
with the evolution of this problem Bioremediation arise because in nature everything is a food
for something else, in bioremediation process the living organism is used in contaminated soil,
water and air to thrive on the wastes in the contaminated area and convert the wastes from toxic
form to another or completely degrading it. Bioremediation has many techniques as in situ or exsitu
techniques on the basis of the pollutants and the type of used technique. Immobilization is
preventing the free movement of enzymes or cells by using a supporter. Using immobilized
enzymes or cells is preferred than using the soluble enzyme because immobilization techniques
have many advantages. The most common method used is entrapment because of its easy,
inexpensive and the polymer formed can be easily divided into particles with the desired size.
Alginate is the supporter matrix as it natural, inert and stable.the objective is toexamine the
bioremediation activity of some pharmaceutical compounds using alginate immobilized
microorganisms and the biodegradation activity of both free and immobilized microorganisms in
addition to studying the different factors affecting the degradation process as well as the stability
of the immobilized cells. Hence, clear of the environment from these wastes in a safe way
through several processes and techniques.