Antidiabetic activity of phenolic compounds from Pecan bark in streptozotocin-induced diabetic rats

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dc.contributor.author M Abdallah, Hossam
dc.contributor.author M Salama, Maha
dc.contributor.author H Abd-Elrahman, Enas
dc.contributor.author A El-Maraghy, Shohda
dc.date.accessioned 2020-03-02T09:33:51Z
dc.date.available 2020-03-02T09:33:51Z
dc.date.issued 2011
dc.identifier.issn 1874-3900
dc.identifier.other https://doi.org/10.1016/j.phytol.2011.07.004
dc.identifier.uri https://cutt.ly/CtqiGIJ
dc.description MSA Google Scholar en_US
dc.description.abstract The n-butanol fraction (BF) of bark of Pecan tree, Carya illinoinensis (Wangenh) K. Koch (Juglandaceae) afforded two new flavonol methyl ether: caryatin-3′ sulfate (6) and caryatin-3′ methyl ether-7-O-β-d-glucoside (7) while five known phenolics (1–5) were isolated from its ethyl acetate fraction (EAF). The structures of isolated compounds were established based on 1D and 2D NMR spectroscopy. The isolated compounds were investigated for their hypoglycaemic, antioxidant as well as the aldose reductase (AR) inhibitory effect in lenses of streptozocin diabetic rats. All the isolated compounds showed significant hypoglycaemic and antioxidant activities, except 5 and 6. A marked AR-inhibitory effect was identified for compounds 2, 3 and 7. en_US
dc.description.sponsorship Elsevir en_US
dc.description.uri https://www.scimagojr.com/journalsearch.php?q=11300153405&tip=sid&clean=0
dc.language.iso en en_US
dc.publisher Elseiver en_US
dc.relation.ispartofseries Phytochemistry Letters;VOL : 4 Issue : 3
dc.subject Pecan bark en_US
dc.subject Aldose reductase en_US
dc.subject Methoxy flavonoids en_US
dc.subject Sulphated flavonoids en_US
dc.subject Antidiabetic en_US
dc.title Antidiabetic activity of phenolic compounds from Pecan bark in streptozotocin-induced diabetic rats en_US
dc.type Article en_US
dc.identifier.doi https://doi.org/10.1016/j.phytol.2011.07.004
dc.Affiliation October University for modern sciences and Arts (MSA)


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