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Browsing Faculty Of Pharmacy Research Paper by Author "Lotfy H.M."

Now showing items 1-20 of 21

Advanced approaches for the treatment and amplification of weak spectral signals produced by critical concentrations in white multicomponent systems

Lotfy H.M.; Saleh S.S.; El-Maraghy C.M. (Elsevier B.V., 2020)

An analytical investigation was carried out to study the treatment and amplification of the spectral signals produced by critical concentrations with high accuracy and precision using two advanced approaches. The ...
Application of three novel spectrophotometric methods manipulating ratio spectra for resolving a pharmaceutical mixture of Chlorphenoxamine hydrochloride and Caffeine

Mohsen A.M.; Lotfy H.M.; Badawey A.M.; Salem H.; Elkhateeb S.Z. (2013)

Three spectrophotometric methods are presented for the determination of a binary mixture of Chlorphenoxaminehydrochloride (CPX) and Caffeine (CAF) in laboratory prepared mixture and pharmaceutical dosage form without prior ...
Column performance study of different variants of liquid chromatographic technique: An application on pharmaceutical ternary mixtures containing tetryzoline

Salem H.; Hassan N.Y.; Lotfy H.M.; Saleh S.S. (Oxford University Press, 2015)

High-performance liquid chromatography (HPLC), ultra-performance liquid chromatography (UPLC) and rapid resolution liquid chromatographic (RRLC) methods have been developed and validated for the separation and quantitation ...
A comparative study of different aspects of manipulating ratio spectra applied for ternary mixtures: Derivative spectrophotometry versus wavelet transform

Salem H.; Lotfy H.M.; Hassan N.Y.; El-Zeiny M.B.; Saleh S.S. (Elsevier, 2015)

This work represents a comparative study of different aspects of manipulating ratio spectra, which are: double divisor ratio spectra derivative (DR-DD), area under curve of derivative ratio (DR-AUC) and its novel approach, ...
Comparative study of new spectrophotometric methods; An application on pharmaceutical binary mixture of ciprofloxacin hydrochloride and hydrocortisone

Lotfy H.M.; Hassan N.; Elgizawy S.M.; Saleh S.S. (Sociedad Chilena de Quimica, 2013)

Simple, specific, accurate and precise spectrophotometric methods were developed and validated for simultaneous estimation of Ciprofloxacin hydrochloride (CIP) and Hydrocortisone (HYD) in their pure form and pharmaceutical ...
A comparative study of novel spectrophotometric methods based on isosbestic points; Application on a pharmaceutical ternary mixture

Lotfy H.M.; Saleh S.S.; Hassan N.Y.; Salem H. (2014)

This work represents the application of the isosbestic points present in different absorption spectra. Three novel spectrophotometric methods were developed, the first method is the absorption subtraction method (AS) ...
A comparative study of progressive versus successive spectrophotometric resolution techniques applied for pharmaceutical ternary mixtures

Saleh S.S.; Lotfy H.M.; Hassan N.Y.; Salem H. (Elsevier, 2014)

This work represents a comparative study of a novel progressive spectrophotometric resolution technique namely, amplitude center method (ACM), versus the well-established successive spectrophotometric resolution techniques ...
A comparative study of smart spectrophotometric methods for simultaneous determination of sitagliptin phosphate and metformin hydrochloride in their binary mixture

Lotfy H.M.; Mohamed D.; Mowaka S. (Elsevier, 2015)

Simple, specific, accurate and precise spectrophotometric methods were developed and validated for the simultaneous determination of the oral antidiabetic drugs; sitagliptin phosphate (STG) and metformin hydrochloride (MET) ...
A comparative study of validated spectrophotometric and TLC- spectrodensitometric methods for the determination of sodium cromoglicate and fluorometholone in ophthalmic solution

Saleh S.S.; Lotfy H.M.; Hassan N.Y.; Elgizawy S.M. (2013)

The determination of sodium cromoglicate (SCG) and fluorometholone (FLU) in ophthalmic solution was developed by simple, sensitive and precise methods. Three spectrophotometric methods were applied: absorptivity factor ...
Computation of geometric representation of novel spectrophotometric methods used for the analysis of minor components in pharmaceutical preparations

Lotfy H.M.; Saleh S.S.; Hassan N.Y.; Salem H. (Elsevier, 2015)

Novel spectrophotometric methods were applied for the determination of the minor component tetryzoline HCl (TZH) in its ternary mixture with ofloxacin (OFX) and prednisolone acetate (PA) in the ratio of (1:5:7.5), and in ...
Design, optimization, and validation of thin-layer chromatography-densitometry and chemometry-assisted spectrophotometry: A comparative study applied on quaternary mixture

Salem H.; Hassan N.Y.; Lotfy H.M.; Saleh S.S. (Akademiai Kiado Rt., 2015)

This work presents a comparative study on the development and validation of two analytical techniques applied for the simultaneous determination of hydrocortisone acetate (HCA), fusidic acid (FSA), methyl paraben (MPB), ...
Development and validation of impurity-profiling UPLC method for the determination of sodium cromoglicate and tetryzoline hydrochloride: Application on rabbit aqueous humor

Lotfy H.M.; Saleh S.S.; Hassan N.Y.; Salem H. (Elsevier, 2015)

Sodium cromoglicate (SCG), antihistaminic agent, and tetryzoline hydrochloride (TZH), a sympathomimetic agent, are formulated together as an ophthalmic preparation. An ultra-performance liquid chromatographic method with ...
Development and validation of simultaneous spectrophotometric and TLC-spectrodensitometric methods for determination of beclomethasone dipropionate and salbutamol in combined dosage form

Samir A.; Lotfy H.M.; Salem H.; Abdelkawy M. (Elsevier, 2014)

Spectrophotometric and TLC-spectrodensitometric methods were developed and validated for the simultaneous determination of beclomethasone dipropionate (BEC) and salbutamol (SAL). The spectrophotometric methods include dual ...
Development of membrane electrodes for the specific determination of tetryzoline hydrochloride in presence of its degradation product in pharmaceutical formulations and biological fluids

Hassan N.Y.; Lotfy H.M.; Saleh S.S.; Salem H. (Center of Excellence in Electrochemistry, Univ. of Tehran, 2015)

Membrane selective electrodes were used to determine tetryzoline hydrochloride (TZH) in pure form, pharmaceutical preparations and in biological fluids. The membrane selective electrodes include construction of water ...
Different mathematical processing of absorption, ratio and derivative spectra for quantification of mixtures containing minor component: An application to the analysis of the recently co-formulated antidiabetic drugs; canagliflozin and metformin

Lotfy H.M.; Mohamed D.; Elshahed M.S. (Elsevier B.V., 2018)

In the presented work several spectrophotometric methods were performed for the quantification of canagliflozin (CGZ) and metformin hydrochloride (MTF) simultaneously in their binary mixture. Two of these methods; response ...
Investigating advanced approaches based on iso-absorptivity coefficient in unresolved spectral signals of binary mixtures

Lotfy H.M.; Saleh S.S. (Hindawi Limited, 2019)

Several spectrophotometric approaches utilize different functions of the iso-absorptivity coefficient in zero-order absorption signals and its manipulated spectra. This work introduced an investigation concerning the ...
Novel two wavelength spectrophotometric methods for simultaneous determination of binary mixtures with severely overlapping spectra

Lotfy H.M.; Saleh S.S.; Hassan N.Y.; Salem H. (MoleculesElsevier B.V., 2015)

This work presents the application of different spectrophotometric techniques based on two wavelengths for the determination of severely overlapped spectral components in a binary mixture without prior separation. Four ...
Novel univariate spectrophotometric determination of the recently released solid dosage form comprising dapagliflozin and saxagliptin via factorized response spectra: Assessment of the average content and dosage unit uniformity of tablets

Lotfy H.M.; Mohamed D.; Elshahed M.S. (Elsevier B.V., 2019)

Dapagliflozin (DPF) and saxagliptin (SXG) are currently co-formulated in a tablet dosage form which is prescribed to improve glycemic control. The absorption spectra of DPF and SXG were highly overlapped which completely ...
Recent development in ultraviolet spectrophotometry through the last decade (2006-2016): A review

Lotfy H.M.; Saleh S.S. (Innovare Academics Sciences Pvt. Ltd, 2016)

Several techniques have been proposed for treatment of spectrophotometric data, with the objective of extracting the largest amount of analytical information from spectra composed of unresolved bands. The instrumental ...
Spectrophotometric methods for simultaneous determination of betamethasone valerate and fusidic acid in their binary mixture

Lotfy H.M.; Salem H.; Abdelkawy M.; Samir A. (Elsevier, 2015)

Five spectrophotometric methods were successfully developed and validated for the determination of betamethasone valerate and fusidic acid in their binary mixture. Those methods are isoabsorptive point method combined with ...

Now showing items 1-20 of 21

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