RP-HPLC determination of three anti-hyperlipidemic drugs in spiked human plasma and in dosage forms

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dc.contributor.author Abdallah O.M.
dc.contributor.other Analytical Chemistry Department
dc.contributor.other Faculty of Pharmacy October
dc.contributor.other University for Modern Sciences and Arts (MSA)
dc.contributor.other El- Wahat Road
dc.contributor.other Egypt
dc.date.accessioned 2020-01-25T19:58:31Z
dc.date.available 2020-01-25T19:58:31Z
dc.date.issued 2011
dc.identifier.issn 9734945
dc.identifier.other https://doi.org/10.1155/2011/376948
dc.identifier.other PubMed ID :
dc.identifier.uri https://t.ly/lWOpV
dc.description Scopus
dc.description.abstract Sensitive, simple and accurate high performance liquid chromatographic (HPLC) methods for the determination of atorvastatin (AT), fluvastatin (FL) and pravastatin (PV) have been developed. The proposed methods involve the use of a 150 mmx4.6 mm Zorbax Extend-C18 column (5 ?m particle size) and different chromatographic conditions for the separation of the three statins. Linearity range was 5-40, 5-30 and 10-60 ?g mL-1 for AT, FL and PV respectively. The developed methods proved to be successful in the determination of all studied drugs in spiked human plasma samples. en_US
dc.language.iso English en_US
dc.publisher Hindawi Limited en_US
dc.relation.ispartofseries E-Journal of Chemistry
dc.relation.ispartofseries 8
dc.subject Atorvastatin en_US
dc.subject Fluvastatin en_US
dc.subject HPLC en_US
dc.subject Pravastatin en_US
dc.title RP-HPLC determination of three anti-hyperlipidemic drugs in spiked human plasma and in dosage forms en_US
dc.type Article en_US
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dcterms.source Scopus
dc.identifier.doi https://doi.org/10.1155/2011/376948
dc.identifier.doi PubMed ID :
dc.Affiliation October University for modern sciences and Arts (MSA)


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