The condensation of active methylene reagents with salicylaldehyde: Novel synthesis of chromene, azaanthracene, pyrano[3,4-c]chromene and chromeno[3,4-c]pyridine derivatives

Abu Elmaati, TM; El-Taweel, FM; Elmougi, SM; Elagamey, A

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The condensation of active methylene reagents with salicylaldehyde: Novel synthesis of chromene, azaanthracene, pyrano[3,4-c]chromene and chromeno[3,4-c]pyridine derivatives

Abu Elmaati, TM; El-Taweel, FM; Elmougi, SM; Elagamey, A

Full Text link: https://cutt.ly/2rxW7wb

Date issued: 2004

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Doi: https://doi.org/10.1002/jhet.5570410502

Publisher: HETERO CORPORATION

Series Info: JOURNAL OF HETEROCYCLIC CHEMISTRY;Volume: 41 Issue: 5 Pages: 655-658

Type: Article

Keywords: pyridine derivatives , chemistry , organic chemistry , chromeno[3,4-c] , pyrano , azaanthracene

Abstract:

On heating of the cyanoacetic acid cyclopentylidene hydrazide I with salicylaldehyde in the presence of bases the azaanthracene derivative 6 was formed. Also, reaction of 3 with malononitrile and ketones 10a,b afforded the pyrano[3,4-c]chromene 9 and chromeno[3,4-c]pyridine 11 respectively. A mechanism for these reactions is proposed