Nano-titania: a novel purification and concentration adsorbent for 125I production for medical uses
Sakr T.M.; Fasih T.W.; Amin M.
Date issued:
2017
Publisher:
Springer Netherlands
Series Info:
Journal of Radioanalytical and Nuclear Chemistry
314
Type:
Article
Keywords:
125I
,
134Cs
,
137Cs
,
Column chromatography
,
Nano-titania
,
Natural xenon
,
Neutron activation
,
adsorbent
,
cesium 134
,
cesium 137
,
cesium ion
,
iodine 125
,
titanium dioxide nanoparticle
,
unclassified drug
,
xenon
,
xenon 124
,
Article
,
brachytherapy
,
chromatography
,
concentration (parameters)
,
controlled study
,
drug purification
,
drug quality
,
elution
,
gamma spectrometry
,
neutron activation analysis
,
nuclear medicine
,
quality control procedures
,
radioactive contamination
,
radioactivity
,
radiochemistry
Abstract:
Abstract: The presented work describes the efficient use of nano-crystalline titania (TiO2) to remove trace levels of cesium radio-contaminants (134Cs and 137Cs) in iodine-125 (125I) solution produced via neutron activation of natural 124Xe target. The adsorption parameters of TiO2 were investigated to attain the optimum purification and concentration conditions of 125I solution. The maximum sorption capacity of Cs and 125I were approximately 56 and 67�mg/g TiO2, respectively. The final 125I solution was of high radiochemical, radionuclidic and chemical purities, besides, it showed high radioactive concentration that confirming its suitability for nuclear medicine applications and 125I brachytherapy sources preparation. Graphical abstract: [Figure not available: see fulltext.]. � 2017, Akad�miai Kiad�, Budapest, Hungary.
Description:
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