Bond Strength and Solubility of a Novel Polydimethylsiloxane-Gutta-Percha Calcium Silicate-Containing Root Canal Sealer

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dc.AffiliationOctober University for modern sciences and Arts (MSA)
dc.contributor.authorKhalil M.M.
dc.contributor.authorAbdelrahman M.H.
dc.contributor.authorEl-Mallah S.
dc.contributor.otherDepartment of Dental Biomaterials
dc.contributor.otherFaculty of Dentistry
dc.contributor.otherFayoum University
dc.contributor.otherEgypt; Department of Dental Biomaterials
dc.contributor.otherFaculty of Dentistry
dc.contributor.otherModern Science and Arts University
dc.contributor.otherCairo
dc.contributor.otherEgypt; Department of Endodontics
dc.contributor.otherFaculty of Dentistry
dc.contributor.otherFayoum University
dc.contributor.otherEgypt
dc.date.accessioned2020-01-09T20:40:38Z
dc.date.available2020-01-09T20:40:38Z
dc.date.issued2019
dc.descriptionScopus
dc.description.abstractBackground. Endodontic sealers are essential for sealing gutta-percha to the dentin walls. They help to ensure that the canal remains free of microorganisms which might lead to infection. In order to perform their intended function, the sealers should properly adhere to the dentin walls and remain insoluble when set in the canal. Objectives. The purpose of this study was to evaluate the bond strength and solubility of a novel polydimethylsiloxane-gutta-percha calcium silicate-containing root canal sealer (GuttaFlow� bioseal) and compare it with the zinc oxide and eugenol sealer (Zical�). Material and methods. The endodontic sealers used in this study were GuttaFlow bioseal and Zical. The bond strength was assessed using push-out bond strength test in 3 root segments: coronal, middle and apical. The solubility was tested according to the American National Standards Institute/American Dental Association (ANSI/ADA) specification No. 57 at 3 different time intervals: 1, 7 and 14 days. Results. The push-out bond strength in all root segments was significantly higher in Zical compared to GuttaFlow bioseal. The solubility was significantly higher on day 1 and 7 in Zical compared to GuttaFlow bioseal, and on day 14, the difference between them was not significant. Conclusions. Within the limitations of this study, the endodontic sealer GuttaFlow bioseal showed low bond strength values compared to Zical. The solubility of the set GuttaFlow bioseal and Zical were both within the recommended ANSI/ADA levels. � 2019 by Wroclaw Medical University.en_US
dc.description.urihttps://www.scimagojr.com/journalsearch.php?q=20500195141&tip=sid&clean=0
dc.identifier.doihttps://doi.org/10.17219/dmp/105626
dc.identifier.doiPubMed ID : 31274254
dc.identifier.issn1644387X
dc.identifier.otherhttps://doi.org/10.17219/dmp/105626
dc.identifier.otherPubMed ID : 31274254
dc.identifier.urihttps://t.ly/W5578
dc.language.isoEnglishen_US
dc.publisherWroclaw Medical Universityen_US
dc.relation.ispartofseriesDental and Medical Problems
dc.relation.ispartofseries56
dc.subjectZinc
dc.subjectHepatitis C
dc.subjectGenotype 4
dc.subjectAnd Egypt introduction
dc.subjectCalcium silicate-con-taining sealeren_US
dc.subjectGuttaFlow biosealen_US
dc.subjectPolydimethylsiloxane-guttapercha sealeren_US
dc.subjectPush-out bond strengthen_US
dc.subjectSolubilityen_US
dc.subjectcalcium silicateen_US
dc.subjectdimeticoneen_US
dc.subjectgutta perchaen_US
dc.subjectroot canal filling materialen_US
dc.subjectzinc oxide eugenolen_US
dc.subjectcalcium derivativeen_US
dc.subjectcalcium silicateen_US
dc.subjectdimeticoneen_US
dc.subjectepoxy resinen_US
dc.subjectgutta perchaen_US
dc.subjectroot canal filling materialen_US
dc.subjectsilicateen_US
dc.subjectArticleen_US
dc.subjectbond strengthen_US
dc.subjectdental cariesen_US
dc.subjectdental parametersen_US
dc.subjectdental restorationen_US
dc.subjectdentinen_US
dc.subjecthumanen_US
dc.subjecthumidityen_US
dc.subjecttooth cementumen_US
dc.subjecttooth root canalen_US
dc.subjectdental pulp cavityen_US
dc.subjectsolubilityen_US
dc.subjectUnited Statesen_US
dc.subjectCalcium Compoundsen_US
dc.subjectDental Pulp Cavityen_US
dc.subjectDimethylpolysiloxanesen_US
dc.subjectEpoxy Resinsen_US
dc.subjectGutta-Perchaen_US
dc.subjectRoot Canal Filling Materialsen_US
dc.subjectSilicatesen_US
dc.subjectSolubilityen_US
dc.subjectUnited Statesen_US
dc.titleBond Strength and Solubility of a Novel Polydimethylsiloxane-Gutta-Percha Calcium Silicate-Containing Root Canal Sealeren_US
dc.typeArticleen_US
dcterms.abstractBackground and Aims: Zinc has been found to be low in chronic hepatitis patients. Its level was correlated with response to Interferon/ribavirin therapy in patients infected with hepatitis C genotype 1. In Egypt, inexpensive predictors to treatment response in Hepatitis C genotype 4 infected patients are desperately needed. We aim to explore if pretreatment zinc serum levels correlate with response to pegylated- interferon and ribavirin therapy in Egyptian patients. Methods: This is an observational prospective study where 57 treatment naïve hepatitis C genotype 4 infected patients that were Hepatitis B and Human Immunodeficiency virus negative were recruited in a hospital setting. The study was performed from October 2010 till June 2012. Patients had Liver biopsy and basic biochemical profiles were performed pretreatment for all patients. Treatment consisted of 48 weeks of pegylated-interferon-alpha2a and ribavirin therapy. Blood samples were withdrawn from 21 healthy subjects to compare zinc levels and other biochemical markers. Patients were followed up to 72 weeks. Results: Pretreatment serum zinc levels were significantly lower in hepatitis C infected patients compared to healthy volunteers (p < 0.05). Moreover, zinc levels correlated to sustained virological response in treated patients (p = 0.00). Conclusion: Serum zinc levels can be used as an inexpensive predictor to effective Pegylated-interferon/ribavirin therapy in Egyptian patients infected with Hepatitic C genotype 4.
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