Abstract:
Origin of African rose (plum) was reported for the first time in china 470 B.C.
these was the first written document about plum. African rose have shown to have lots
of medical uses and also have the ability to prevent diseases related to food, also in
promoting of health. Moreover, African rose have been considered as a therapeutic
treatment for pathologies that are associated with inflammation and oxidative stress. It
was reveal that African rose phenolic compounds have so many of biological
activities such as anti-inflammatory, anticancer, antioxidant and antimicrobial
activities.
The recent study is to analysis in vitro antimicrobial, anticancer and
antioxidant activities of phenols, tannins, flavonoids and alkaloids that were extracted
from African rose. These extractions were used to extract phenolic compounds from
African rose this is done by ethanolic extraction method. Then to determine the
phytochemicals HPLC analysis was used, DPPH was used to evaluate antioxidant
activity, to determine antimicrobial activity agar discs diffusion method was used.
There were three different cancer cell lines that had been taken from human there are
Liver cell line (HepG2), Brest cancer cell line (MCF-7) and colon cancer cell line
(Caco-2) colon cancer these to determine cytotoxic activity beside using of neutral red
(NR) assay.