dc.contributor.author |
Mohamed Kamal Ismail Abo-El-Youssr, Yehia |
|
dc.date.accessioned |
2020-10-12T11:28:20Z |
|
dc.date.available |
2020-10-12T11:28:20Z |
|
dc.date.issued |
2020 |
|
dc.identifier.citation |
Copyright © 2020 MSA University. All Rights Reserved. |
en_US |
dc.identifier.uri |
http://repository.msa.edu.eg/xmlui/handle/123456789/3872 |
|
dc.description |
Faculty Of Biotechnology Graduation Project 2019 - 2020 |
en_US |
dc.description.abstract |
Interleukin 4 (IL-4) is a cytokine which is encoded by IL4 gene, it plays a role to activate the differentiation of the native T helper cells (Th0) into a normal T-helper 2 cells (Th2). Previous researches had shown that IL-4 protects the pancreatic islets from cytotoxicity that can occur as well as it decreases the production of (Th1). In addition, single nucleotide polymorphism (SNP) in the IL-4 promoter region (IL4-590 C>T) could have a relation with type two diabetes mellitus (T2DM). In addition to that, the long-term exposure of IL-4 on the pancreatic islets can inhibit islet functions. The aim of the present study is to probe for the association of IL4-590 C>T with TDM in Egyptian patients. |
en_US |
dc.description.sponsorship |
External/Internal Supervisor
Dr. Hossam Taha Mohamed |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
October University for Modern Sciences and Arts |
en_US |
dc.relation.ispartofseries |
Faculty Of Biotechnology Graduation Project 2020; |
|
dc.subject |
MSA |
en_US |
dc.subject |
October University for Modern Sciences and Arts |
en_US |
dc.subject |
University for Modern Sciences and Arts |
en_US |
dc.subject |
جامعة أكتوبر للعلوم الحديثة والآداب |
en_US |
dc.subject |
Biotechnology |
en_US |
dc.subject |
polymorphisms |
en_US |
dc.title |
Association between the frequency of IL-4 590C>T gene polymorphisms and susceptibility to type 2 diabetes mellitus. |
en_US |
dc.type |
Other |
en_US |
dc.Affiliation |
October University for modern sciences and Arts (MSA) |
|