Abstract:
Since beginning of night’s diabetes mellitus has been
considered the main systemic disease that affects the periodontium, American Diabetes Association (ADA) has added
periodontal disease as the 6 thcomplication of diabetes. Diabetes attacks the periodontium and cooperate with periodontal
microorganisms to induce rapid and severe attachment loss
& alveolar bone resorption. Chronic hyperglycemia has negative pathological effects on periodontal tissues through many
mechanisms as qualitative change of some subgingival pathogenic microorganisms, decreased salivation, disturbance of
neutrophils functions, vascular changes, (AGE) accumulation
in periodontal tissues, exaggerated production of prostaglandins
and excessive generation of free radicals. Therefore, understanding of all these mechanisms is the first and the most
important step in the management and better periodontal
treatment outcome.