The present study aimed to evaluate the
anticancer activity of methanol/ ethanol Orange
Albedo extracts where test extracts showed antiproliferative activity.
Also, the test extract viability % were concentration,
IC50 value and cell type dependent. Also, there was a
significant up / down regulation of pro/ anti
apoptotic genes. Also the cell cycle profile indicated
cell arrest at the G2 / M phase compared with the
control accompanied with apoptotic profile
significantly elevated than non treated cell control
(P<0.05).