Abstract:
Higher plants have been utilized worldwide as characteristic drug a long time to cure human diseases. About 80% of
individuals globally use plants as safe sources of medication to cure human diseases through completely different medicine
system. One of the available indigenous medicinal plants, Ficus sycomorus belongs to the Moraceae family. The plant contains
totally different teams of biologically active compounds that square measure chargeable for the biological activity. Ethanolic
and ethyl acetate extracts of leaves of Ficus sycomorus contain higher concentrations of total phenols, flavonoids, tannins,
alkaloids and steroids than the fruit extracts. Ethanolic extract in both fruits and leaves gave higher concentrations of
phytochemical compounds than the ethyl acetate extracts. Therefore, fruit and leaves extract have antioxidant and
antimicrobial activity against gram positive, negative bacteria and fungus. Also, the percentage of Liver cell line (HepG2),
Colorectal adenocarcinoma (Caco-2) and Breast cell line (MCF-7) viability was decreased with increasing the concentrations
of the ethanolic extract of fruits and leaves of Ficus sycomorus. The high concentrations of ethanolic extract of fruits caused
high reduction in the viability of cancer cells, especially in Colorectal adenocarcinoma (Caco-2) cell line. In addition,
phytochemical compound screened by GC-MS method. In GC-MS analysis, 12 bioactive phytochemical compounds were
identified in fruits and 29 bioactive compounds were detected in leaves extract. These totally different active phytochemicals
are found to possess a good vary of activities, which can facilitate within the protection against incurable diseases.