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Browsing by Author "October City"

Now showing items 1-20 of 37

Anti-tumor and anti-leishmanial evaluations of 1,3,4-oxadiazine, pyran derivatives derived from cross-coupling reactions of ?-bromo-6H-1,3,4- oxadiazine derivatives

Mohareb R.M.; Schatz J. (2011)

Cyanoacetylhydrazine reacted with the ?-bromoacetophenones 2a,b to give hydrazide-hydrazone derivatives 3a,b. The latter products were cyclized to the 1,3,4-oxadiazine derivatives 4a,b. Bromination of the latter products ...
Cathepsin D expression in chronic plaque psoriasis: An immunohistochemical study

Abdou A.G.; Maraee A.H.; Shoeib M.A.E.; Elsammie A.A.A.; Elnaidany N.F. (2011)

Cathepsins are lysosomal cysteine proteases, which are involved in a variety of physiologic processes such as proenzyme activation, antigen presentation, tissue remodeling, bone matrix resorption, and pathologic processes ...
Co(II), Ni(II) and Cu(II) complexes of azo-aminopyrazole ligand: Spectroscopic, crystal structure and quantum chemical calculations

Abdel-Ghani N.T.; Mansour A.M.; Abo El-Ghar M.F.; El-Borady O.M.; Shorafa H. (Elsevier S.A., 2015)

Reaction of 5-Methyl-4-(2-nitro-phenylazo)-2-phenyl-2H-pyrazol-3-ylamine (H<inf>2</inf>L) with Co(II), Ni(II) and Cu(II) salts affords complexes of the type [M(HL)<inf>2</inf>], which were characterized by elemental analysis, ...
Comparative study of reversed-phase high-performance liquid chromatography versus thin-layer chromatography-densitometry for determination of Citicoline sodium in presence of its alkaline degradation products

Mahmoud O.A.; Hegazy M.A.; Salem H.; Moustafa A.A. (Akademiai Kiado Rt., 2015)

Simple, sensitive, selective, and precise stability-indicating thin-layer chromatography (TLC)-densitometric and reversed-phase high-performance liquid chromatography (RP-HPLC) methods were developed and validated for the ...
A comparative study of smart spectrophotometric methods for simultaneous determination of a skeletal muscle relaxant and an analgesic in combined dosage form

Salem H.; Mohamed D. (Elsevier, 2015)

Six simple, specific, accurate and precise spectrophotometric methods were developed and validated for the simultaneous determination of the analgesic drug; paracetamol (PARA) and the skeletal muscle relaxant; dantrolene ...
A comparative study of smart spectrophotometric methods for simultaneous determination of sitagliptin phosphate and metformin hydrochloride in their binary mixture

Lotfy H.M.; Mohamed D.; Mowaka S. (Elsevier, 2015)

Simple, specific, accurate and precise spectrophotometric methods were developed and validated for the simultaneous determination of the oral antidiabetic drugs; sitagliptin phosphate (STG) and metformin hydrochloride (MET) ...
Cytotoxicity and gene expression profiles of novel synthesized steroid derivatives as chemotherapeutic anti-breast cancer agents

Elmegeed G.A.; Khalil W.K.B.; Mohareb R.M.; Ahmed H.H.; Abd-Elhalim M.M.; Elsayed G.H. (2011)

Anti-cancer agents which combine two biologically active compounds in one such as steroidal heterocyclic derivatives attain both hormone and cytotoxic effects on cancer cells. The aim of the present study is to synthesize ...
Design and synthesis of novel antimicrobial acyclic and heterocyclic dyes and their precursors for dyeing and/or textile finishing based on 2-n-acylamino-4,5,6,7-tetrahydrobenzo[b]thiophene systems

Shams H.Z.; Mohareb R.M.; Helal M.H.; Mahmoud A.E.-S. (2011)

A series of novel polyfunctionalized acyclic and heterocyclic dye precursors and their respective azo (hydrazone) counterpart dyes and dye precursors based on conjugate enaminones and/or enaminonitrile moieties were ...
Design, optimization, and validation of thin-layer chromatography-densitometry and chemometry-assisted spectrophotometry: A comparative study applied on quaternary mixture

Salem H.; Hassan N.Y.; Lotfy H.M.; Saleh S.S. (Akademiai Kiado Rt., 2015)

This work presents a comparative study on the development and validation of two analytical techniques applied for the simultaneous determination of hydrocortisone acetate (HCA), fusidic acid (FSA), methyl paraben (MPB), ...
Development of new indole-derived neuroprotective agents

Mohareb R.M.; Ahmed H.H.; Elmegeed G.A.; Abd-Elhalim M.M.; Shafic R.W. (2011)

There is a great deal of interest in neurotrophin therapy to prevent neuronal degeneration. The present study aimed at synthesizing new functionalized indole derivatives with structures justifying neuroprotective activity ...
Diagnostic and prognostic role of galectin 3 expression in cutaneous melanoma

Abdou A.G.; Hammam M.A.; Farargy S.E.; Farag A.G.A.; El Shafey E.N.; Farouk S.; Elnaidany N.F. (2010)

Many of the histopathologic criteria used to diagnose melanoma overlap with atypical but otherwise benign naevi such as dysplastic or Spitz naevi. Galectin-3 is a member of the galectin gene family and is expressed at ...
Electrochemical behavior of Al 2 O 3 /Al composite coated Al electrodes through surface mechanical alloying in alkaline media

Ebrahim M.R.; Shehata O.S.; Abdel Fatah A.H. (International Journal of Pharmacognosy and Phytochemical ResearchElsevier B.V., 2019)

The behavior of Al 2 O 3 /Al composite coated Al electrodes fabricated by surface mechanical alloying 'sMA� was studied. The work was accomplished using Cyclic voltammetry and electrochemical impedance spectroscopy (EIS) ...
Epidemiology of dermatophyte infections among school children in Menoufia Governorate, Egypt

Farag A.G.A.; Hammam M.A.; Ibrahem R.A.; Mahfouz R.Z.; Elnaidany N.F.; Qutubuddin M.; Tolba R.R.E. (Blackwell Publishing Ltd, 2018)

Most superficial mycotic infections of human skin are due to dermatophytes. Children are frequently affected due to different predisposing factors, particularly overcrowding in classrooms. This study aimed to estimate the ...
Evaluation of anti-inflammatory, anti-nociceptive, and anti-ulcerogenic activities of novel synthesized thiazolyl and pyrrolyl steroids

Mohareb R.M.; Elmegeed G.A.; Baiuomy A.R.; Eskander E.F.; William M.G. (2011)

Developing new therapeutic agents that can overcome gastrointestinal injury and at the same time could lead to an enhanced anti-inflammatory effect becomes an urgent need for inflammation patients. Thiazolyl and pyrrolyl ...
Helicobacter pylori infection in patients with chronic urticaria: Correlation with pathologic findings in gastric biopsies

Abdou A.G.; Elshayeb E.I.; Farag A.G.A.; Elnaidany N.F. (2009)

Background: Chronic urticaria is a persistent urticaria lasting longer than 6.weeks, affecting 20% of the general population. Various infectious agents have been reported as causes of urticaria, including Helicobacter ...
IL-8 mRNA and serum levels in vitiligo patients: A case control study

Farag A.G.; Marae A.H.; Habib M.S.E.; Mahfouz R.Z.; Elnaidany N.F.; Youssef S.I.; El-Feky S.M. (Oxford University PressJournal of Clinical and Diagnostic Research, 2017)

Introduction: Many theories are suggested to explain aetiology of vitiligo, such as autoimmune, genetic and biochemical. Interleukin-8 (IL-8) is a pro-inflammatory chemokine which is evaluated in the pathogenesis of some ...
Industrial development and the trade-off to environment: Measurement techniques, meanings and outcomes in the context of water poverty in Egypt

Salman D. (2011)

Industrialisation is one of the main pillars of economic development but it is usually associated with significantly negative impacts on the environment. Environmental damage impedes development efforts; destroys resources; ...
Is Vitamin D a participant in narrow-band ultraviolet B-induced pigmentation in patients with vitiligo?

Farag A.G.A.; Haggag M.M.; Muharram N.M.; Mahfouz R.; Elnaidany N.F.; Abd El Ghany H.M. (Lippincott Williams and Wilkins, 2018)

Background Because of its safety and efficacy, narrow-band ultraviolet B (NBUVB) therapy has found importance in vitiligo treatment. NBUVB may promote pigmentation in vitiligo through provoked vitamin D synthesis. However, ...
Novel synthesis and antitumor evaluation of polyfunctionally substituted heterocyclic compounds derived from 2-cyano-N-(3-cyano-4,5,6,7- tetrahydrobenzo[b]thiophen-2-yl)-acetamide

Shams H.Z.; Mohareb R.M.; Helal M.H.; Mahmoud A.E. (2011)

The reaction of 2-amino-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene with ethyl cyanoacetate gave 2-cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2- yl)-acetamide. The latter was used to synthesize different heterocyclic ...
Novel synthesis of hydrazide-hydrazone derivatives and their utilization in the synthesis of coumarin, pyridine, thiazole and thiophene derivatives with antitumor activity

Mohareb R.M.; Fleita D.H.; Sakka O.K. (2011)

The reaction of cyanoacetyl hydrazine (1) with 3-acetylpyridine (2) gave the hydrazide-hydrazone derivative 3. The latter compound undergoes a series of heterocyclization reactions to give new heterocyclic compounds. The ...

Now showing items 1-20 of 37

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