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Browsing by Author "M Nissan, Yassin"

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Antimicrobial and anticancer activity of some novel fluorinated thiourea derivatives carrying sulfonamide moieties: synthesis, biological evaluation and molecular docking

M Ghorab, Mostafa; S Alsaid, Mansour; SA El-Gaby, Mohamed; M Elaasser, Mahmoud; M Nissan, Yassin (SPRINGER, 2017)

Various thiourea derivatives have been used as starting materials for compounds with better biological activities. Molecular modeling tools are used to explore their mechanism of action.
Novel 4-(4-substituted-thiazol-2-ylamino)-N-(pyridin-2-yl)-benzenesulfonamides as cytotoxic and radiosensitizing agents

M Ghorab, Mostafa; A Ragab, Fatma; I Heiba, Helmy; M Agha, Hebaallah; M Nissan, Yassin (SPRINGER, 2012)

A series of novel 4-(4-substituted-thiazol-2-ylamino)-N-(pyridin-2-yl) benzene-sulfonamides were synthesized and screened for their cytotoxic activity against human breast cancer cell line (MCF-7). Compounds 6, 7, 9, 10, ...
Novel brominated quinoline and pyrimidoquinoline derivatives as potential cytotoxic agents with synergistic effects of γ-radiation

M Ghorab, Mostafa; A Ragab, Fatma; I Heiba, Helmi; M Nissan, Yassin; M Ghorab, Walid (Pharmaceutical Society of Korea, 2012)

New quinoline derivatives 6, 7 and 19, pyrimidoquinoline derivatives 8–16 and triazolopyrimidoquinoline derivatives 17 and 18 bearing a bromo-substituent were synthesized starting from 3-(4-Bromophenylamino)-5,5-dimethyl ...
Novel pyrazolopyrimidines: Synthesis, in vitro cytotoxic activity and mechanistic investigation

S Hassan, Ghaneya; E Abdel Rahman, Doaa; M Nissan, Yassin; A Abdelmajeed, Esraa; M Abdelghany, Tamer (ELSEVIER, 2017)

A series of novel pyrazolo[3,4-d]pyrimidines bearing benzenesulfonamide moiety 5a-f, 6 and 7 were synthesized. Cytotoxic screening was conducted against MCF-7 and HepG2. 6-(4-Methoxyphenyl)-4-oxopyrazolopyrimidine derivative ...
Synthesis and anticancer activity of some novel trifluoromethylquinolines carrying a biologically active benzenesulfonamide moiety

S Al-Dosari, Mohammed; M Ghorab, Mostafa; S AlSaid, Mansour; M Nissan, Yassin; B Ahmed, Abdulkareem (ELSEVIER, 2013)

Several trifluoromethylquinoline derivatives containing a biologically active benzenesulfonamide moiety 2–14, 16, urea derivatives 15, 17, 4-isothiocyanate 18 and the corresponding carbamimidothioic acid derivatives 19–30, ...

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Browsing by Author "M Nissan, Yassin"

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