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Browsing by Author "M Aref, Ahmed"

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Cinnamic acid Attenuates Cisplatin-Induced Hepatotoxicity and Nephrotoxicity

A Tohamy, Amany; M Aref, Ahmed; E Abdel Moneim, Ahmed; H Sayed, Romissaa (Journal of Basic and Environmental Sciences, 2016)

We investigated the effects of cinnamic acid (CA, 20 mg/kg body weight) oncisplatin (CP)-induced hepto and nephrotoxicity in mice. CP (5 mg/kg bwt)wasinjected intraperitoneally and CA was given by ...
Expression of p53 Protein in Hepatocellular Carcinoma: Relationships to Viral Infection and Prognostic Factors

E Helal, Thanaa; A El-Ganzuri, Monir; M Aref, Ahmed; T Badr, Mohamed (Received: 17 January, 2010. Accepted: 11 May, 2010.Original Research PaperDynamic Biochemistry, Process Biotechnology and Molecular Biology ©2010 Global Science Book, 2010)

Hepatocellular carcinoma (HCC) is very common in Egypt due to the high incidence of hepatitis C virus (HCV) infection. The aim of the current study was to assess the relationships between p53 and the viral infection as ...
hca519/TPX2: a potential T-cell tumor-associated antigen for human hepatocellular carcinoma

M Aref, Ahmed; T Hoa, Neil; Ge, Lisheng; Agrawal, Anshu; Dacosta-Iyer, Maria; Lambrecht, Nils; Ouyang, Yi; N Cornforth, Andrew; R Jadus, Martin (Dove Press, 2014)

Immunotherapy for human hepatocellular cancer (HCC) is slowly making progress towards treating these fatal cancers. The identification of new antigens can improve this approach. We describe a possible new antigen, ...
The Potential Role ofAzadirachta indicaTreatment onCisplatin-Induced Hepatotoxicity and Oxidative Stressin Female Rats

M Aref, Ahmed; A Dkhil, Mohamed; Al-Quraishy, Saleh; S Othman, Mohamed; M. El-Deib, Kamal; E Abdel Moneim, Ahmed (Hindawi, 2013)

Azadirachta indica A. Juss. (neem, family: Meliaceae) is perhaps the most commonly used traditional medicinal plant of India. In this study we investigated the protective effect of methanolic neem leaves extract (MNLE; ...
Rutin and Selenium Co-administration Reverse 3-Nitropropionic Acid-Induced Neurochemical and Molecular Impairments in a Mouse Model of Huntington’s Diseas

S Abdelfattah, Mohamed; EA Badr, Sherif; A Lotfy, Sally; H Attia, Gouda; M Aref, Ahmed; E Abdel Moneim, Ahmed; B Kassab, Rami (SPRINGER, 2020)

Systemic administration of 3-nitropropionic acid (3-NPA) is commonly used to induce Huntington’s disease (HD)-like symptoms in experimental animals. Here, the potential neuroprotective efficiency of rutin and selenium (RSe) ...
Serum Levels of Interleukin-6 and Interleukin-10 as Biomarkers for Hepatocellular Carcinoma in Egyptian Patients

M Aref, Ahmed; S Othman, Mohamed; A Mohamed, Amal; A Ibrahim, Wesam (Hindawi Publishing Corporation, 2015)

Interleukin-10 (IL-10) and interleukin-6 (IL-6) have been reported to be related to hepatocellular carcinoma (HCC) prognosis. This study aimed to investigate the clinical usefulness of serum levels of IL-6 and IL-10 as ...

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