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Browsing by Author "K Chopin, Dominique"

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Gefitinib Inhibits the Growth and Invasion of Urothelial Carcinoma Cell Lines in which Akt and MAPK Activation Is Dependent on Constitutive Epidermal Growth Factor Receptor Activation

Nicolle, Gaëlle; Daher, Ahmed; Maillé, Pascale; Vermey, Marcel; Loric, Sylvain; Bakkar, Ashraf; Wallerand, Hervé; Vordos, Dimitrios; Vacherot, Francis; Gil Diez De Medina, Sixtina; C Abbou, Claude; Van der Kwast, Theodore; Thiery, Jean-Paul; Radvanyi, François; K Chopin, Dominique (American Association for Cancer Research, 2006)

Abnormally high levels of epidermal growth factor receptor (EGFR) protein are associated with advanced tumor stage/grade. The objective of this study was to evaluate the effects of the specific EGFR tyrosine kinase inhibitor ...
Mutations in TP53 , but not FGFR3 , in urothelial cell carcinoma of the bladder are influenced by smoking: contribution of exogenous versus endogenous carcinogens

Wallerand, Hervé; A Bakkar, Ashraf; Gil Diez De Medina, Sixtina; Pairon, Jean-Claude; Ching Yang, Yu; Vordos, Dimitri; Bittard, Hugues; Fauconnet, Sylvie; Kouyoumdjian, Jean-Claude; Claude Jaurand, Marie; Feng Zhang, Zuo; Radvanyi, François; Thiery, Jean-Paul; K Chopin, Dominique (Oxford University Press, 2005)

Smoking is a major risk factor for urothelial cell carcinoma of the bladder (UCC). Mutations in the FGFR3 and TP53 genes have been shown to define two distinct pathways in superficial papillary and invasive UCC disease, ...
Occupational exposure to polycyclic aromatic hydrocarbons influenced neither the frequency nor the spectrum of FGFR3 mutations in bladder urothelial carcinoma

A Bakkar, Ashraf; Allory, Yves; Iwatsubo, Yuriko; Gil Diez De Medina, Sixtina; Maille, Pascale; Khreich, Nathalie; Riou, Audrey; Leroy, Karen; Vordos, Dimitrios; C Abbou, Claude; Andujar, Pascale; Billebaud, Thierry; Chammings, Soizick; Conso, Françoise; De La Taille, Alexandre; Fontaine, Eric; Gattegno, Bernard; Ravery, Vincent; Sibony, Mathilde; Radvanyi, François; K Chopin, Dominique; Pairon, Jean‐Claude (Wiley Subscription Services, Inc., A Wiley Company, 2010)

Occupational exposure to polycyclic aromatic hydrocarbons (PAH) is associated with an increased risk of urothelial carcinoma (UC). FGFR3 is found mutated in about 70% of Ta tumors, which represent the major group at ...
Sensitive Allele-Specific PCR Assay Able to Detect FGFR3 Mutations in Tumors and Urine from Patients with Urothelial Cell Carcinoma of the Bladder

A Bakkar, Ashraf; Quach, Viviane; Le Borgne, Anaïg; Toublanc, Marianne; Henin, Dominique; Wallerand, Hervé; Radvanyi, François; Bittard, Hugues; Ravery, Vincent; Boccon Gibod, Laurent; Gil Diez de Medina, Sixtina; K Chopin, Dominique; Grandchamp, Bernard (Oxford University Press, 2005)

Activating somatic point mutations in exons 7, 10, and 15 of the FGFR3 gene are frequently observed in urothelial cell carcinoma (UCC) (1)(2). These mutations have been found primarily in superficial papillary pTa tumors ...

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Browsing by Author "K Chopin, Dominique"

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