Salaheldin, Ahmed M Abdel Wahed , ManalSaleh, Neven2024-07-242024-07-242023-08https://doi.org/10.21203/rs.3.rs-3262058/v1http://repository.msa.edu.eg/xmlui/handle/123456789/6107The prevalence of vision impairment is rising at an alarming rate. The goal of the study is to create an automated method that uses Optical Coherence Tomography (OCT) to classify retinal disorders into four categories, namely, Choroidal Neovascularization, Diabetic Macular Edema, Drusen, and normal cases. The study proposed a new framework that combines machine learning and deep learning-based techniques. The utilized classifi ers were Support Vector Machine (SVM), K-Nearest Neighbor (K-NN), Decision Tree (DT), and Ensemble Model (EM). A feature extractor was also employed, which was the InceptionV3 convolutional neural network. The performance of the models has been measured over nine criteria using a dataset of 18000 OCT images. For the SVM, K-NN, DT, and EM, the analysis exhibited state-of-the-art performance with classifi cation accuracies of 99.43%, 99.54%, 97.98%, and 99.31%, respectively. A promising methodology has been introduced for the automatic identifi cation and classifi cation of retinal disorders leading to reducing human error and saving time alike.endecision tree; ensemble model; K-nearest neighbor; optical coherence tomography; retinal disorders; support vector machineArticlehttps://doi.org/10.21203/rs.3.rs-3262058/v1