Shaaban M.A.-E.Kamal A.M.Teba H.E.-S.Pharmaceutical Organic Chemistry DepartmentFaculty of PharmacyCairo UniversityCairo11561Egypt; Pharmaceutical Organic Chemistry DepartmentFaculty of PharmacyOctober University for Modern Sciences and Arts (MSA)CairoEgypt2020-01-092020-01-09201617475198https://doi.org/10.3184/174751916X14577069096465PubMed ID :https://t.ly/MXrM3ScopusTwenty two new polycyclic compounds containing a 2-substituted benzimidazole core were synthesised, characterised and evaluated in vitro against the three most widespread cancers. Seven compounds showed outstanding antitumor activity towards breast, lung or central nervous system cancer cell lines.EnglishOctober University for Modern Sciences and Artsجامعة أكتوبر للعلوم الحديثة والآدابUniversity of Modern Sciences and ArtsMSA University2-substituted benzimidazole derivativesAnticancer agentsHeterocyclic synthesisNucleophilic reactionsSynthesis, characterisation and biological screening of some 2-substituted benzimidazole derivatives as potential anticancer agentsArticlehttps://doi.org/10.3184/174751916X14577069096465PubMed ID :