Hosny, Manal MYussif, Nermin M2019-12-252019-12-252017-060306-9877https://doi.org/10.1016/j.mehy.2017.04.014https://www.ncbi.nlm.nih.gov/pubmed/28571797Accession Number: WOS:000403731600029Aggressive periodontitis is an enigmatic periodontal disease that characterized by advanced undeterminable periods of tissue destruction in a limited time period. It gets along well to young individuals with successive periods of disease activity. 2 Aggressive bone destruction usually associated with limited plaque and calculus deposits. According to microbial theory, facultative and obligate gram negative anaerobic bacteria as Aggregatibacter actinomycetemcomitans (A.a) and Porphyromonas gingivalis (P. G) and etc are usually claimed for such diseaseen-USUniversity for HEALTHTHERAPYVITAMIN-CArticlehttps://doi.org/10.1016/j.mehy.2017.04.014