El-Taweel, F. M. A.Abou Elmaaty, T. M.2019-12-052019-12-052016Cited References in Web of Science Core Collection: 550022-152Xhttps://doi.org/10.1002/jhet.2340https://cutt.ly/Re8yGduAccession Number: WOS:000374982900001This review deals with the synthetic potentiality and utility of antipyrine and its derivatives in the synthesis of 4-substituted antipyrine and other heterocycles containing antipyrine moiety such as thiazole, pyrazolopyridines, pyrazolopyrimidines, and pyrazolotriazines. The reactions that cover the methods of synthesizing the aforementioned heterocycles such as addition, condensation, and cyclization were also reviewed.enANTIMICROBIAL ACTIVITIESPYRIDINE-DERIVATIVESACTIVATED NITRILESSCHIFF-BASESCHEMISTRYHIAZOLEPYRAZOLEPYRAZOLO<1,5-A>PYRIMIDINEANTIBACTERIALMETABOLITESArticlehttps://doi.org/10.1002/jhet.2340