Sakr, TM2020-02-122020-02-1220141066-3622https://doi.org/10.1134/S1066362214020131https://cutt.ly/RrJOVgPMSA Google ScholarRadioiodinated N-(3-iodophenyl)-2-methylpyrimidine-4,6-diamine (radioiodinated IPMPD), a potential lung scintigraphic agent, was synthesized via direct electrophilic substitution. Factors affecting the radiochemical yield were studied in detail. High radiochemical yield (92.3 ± 2.3%) was reached. The compound is stable in vitro for 24 h. Radioiodinated IPMPD was biologically evaluated in normal Albino mice. The compound demonstrated high lung uptake (21.4 ± 1.7% of injected dose per gram organ at 15 min) and thus shows promise for lung perfusion scintigraphyenHOClLung PerfusionRadiochemical YieldLung ScintigraphyAtomic Energy AuthorityArticlehttps://doi.org/10.1134/S1066362214020131