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Polymerization shrinkage and release of thermal stresses are the major disadvantages exhibited by the material. In an attempt to overcome dimensional in accuracies of PMMA resin, new thermoplastic resins and alternative processing techniques have been developed. Purpose: The purpose of this study was to evaluate and compare the adaption accuracy of two commercial heat cured resins and an injection molded resin. Materials and Methods: a total of 21 accurate denture bases with the same dimension were fabricated, 14 denture bases were made using conventional compression molding technique (Acrostone, WHW plastic, England and Vertex regular, Zeist, Netherlands), and 7 dentures were processed using injection molding technique (Crystal, Bredent, Germany). The adaptation accuracy was examined using universal measuring microscope. The gap between the resin base and stone cast was measured at canine region and posterior palatal area at five points at 5 points, corresponding to the right and left residual ridge crests, the midline, and the right and left marginal limits of the flanges. Results: The least total gap score measured was for Bre-Crystal followed by Vertex- regular while the highest gap score was for Acrostone group. However, there was no statistically significant difference between the Vertex- regular and Acrostone groups. Conclusion: injection moulded PMMA resin showed superior dimensional accuracy compared to conventional pressure packed PMMA resin.enGap measurementHeat cured resinInjection molded resinArticle