Zaki, Bishoy MaherFahmy, Nada AAziz, Ramy KaramSamir, RehamEl-Shibiny, Ayman2023-01-252023-01-252023-01https://doi.org/10.3389/fcimb.2023.1077995http://repository.msa.edu.eg/xmlui/handle/123456789/5326The rise of infections by antibiotic-resistant bacterial pathogens is alarming. Among these, Klebsiella pneumoniae is a leading cause of death by hospital-acquired infections, and its multidrug-resistant strains are flagged as a global threat to human health, which necessitates finding novel antibiotics or alternative therapies. One promising therapeutic alternative is the use of virulent bacteriophages, which specifically target bacteria and coevolve with them to overcome potential resistance. Here, we aimed to discover specific bacteriophages with therapeutic potential against multiresistant K. pneumoniae clinical isolates.en-USgenomelyticanti-biofilmmultidrug-resistantKlebsiella pneumoniaeCharacterization and comprehensive genome analysis of novel bacteriophage, vB_Kpn_ZCKp20p, with lytic and anti-biofilm potential against clinical multidrug-resistant Klebsiella pneumoniaeArticlehttps://doi.org/10.3389/fcimb.2023.1077995