El-Dawla, Nada M. QamarSallam, Al-Aliaa MEl-Hefnawy, Mohamed HEl-Mesallamy, Hala O2019-11-142019-11-142019-081342-1751https://doi.org/https://cutt.ly/peGPvNLAccession Number: WOS:000475963400009Results Concerning E-cadherin levels, in comparison to control group, there were significantly decreased in all groups (0.94, 0.52, and 0.14 ng/mL in normoalbuminuria, microalbuminuria, and macroalbuminuria groups; respectively). For periostin levels, nonsignificant increase in normoalbuminuria (0.32 ng/mL) than control group (0.3 ng/mL) was observed. There was a significant increase in other groups with the highest values in macroalbuminuria group (1.66 ng/mL). E-cadherin and periostin were correlated with each other (r = -0.353, P < 0.001). UACR was negatively correlated with E-cadherin and positively correlated with periostin. ROC curve analyses showed that the AUC to diagnose established microalbuminuria using E-cadherin was 0.998 (95% CI 0.932-1), and using periostin was 0.833 (95% CI 0.709-0.919).en-USTISSUEEXPRESSIONMECHANISMSIDENTIFICATIONBIOMARKERPlus:RENAL INJURYPeriostinEMTE-cadherinDiabetic nephropathyE-cadherin and periostin in early detection and progression of diabetic nephropathy: epithelial-to-mesenchymal transitionArticlehttps://doi.org/