Sakr T.M.Fasih T.W.Amin M.Radioactive Isotopes and Generators DepartmentHot Laboratories CentreAtomic Energy AuthorityCairo13759Egypt; Pharmaceutical Chemistry DepartmentFaculty of PharmacyOctober University of Modern Sciences and Arts (MSA)GizaEgypt2020-01-092020-01-0920172365731https://doi.org/10.1007/s10967-017-5439-zPubMed ID :https://t.ly/KXMnPScopusMSA Google ScholarAbstract: The presented work describes the efficient use of nano-crystalline titania (TiO2) to remove trace levels of cesium radio-contaminants (134Cs and 137Cs) in iodine-125 (125I) solution produced via neutron activation of natural 124Xe target. The adsorption parameters of TiO2 were investigated to attain the optimum purification and concentration conditions of 125I solution. The maximum sorption capacity of Cs and 125I were approximately 56 and 67�mg/g TiO2, respectively. The final 125I solution was of high radiochemical, radionuclidic and chemical purities, besides, it showed high radioactive concentration that confirming its suitability for nuclear medicine applications and 125I brachytherapy sources preparation. Graphical abstract: [Figure not available: see fulltext.]. � 2017, Akad�miai Kiad�, Budapest, Hungary.English125I134Cs137CsColumn chromatographyNano-titaniaNatural xenonNeutron activationadsorbentcesium 134cesium 137cesium ioniodine 125titanium dioxide nanoparticleunclassified drugxenonxenon 124Articlebrachytherapychromatographyconcentration (parameters)controlled studydrug purificationdrug qualityelutiongamma spectrometryneutron activation analysisnuclear medicinequality control proceduresradioactive contaminationradioactivityradiochemistryArticlehttps://doi.org/10.1007/s10967-017-5439-zPubMed ID :