Abu Nawareg M.Elkassas D.Zidan A.Abuelenain D.Abu Haimed T.Hassan A.H.Chiba A.Bock T.Agee K.Pashley D.H.Department of Restorative DentistryFaculty of DentistryKing Abdulaziz UniversityJeddahSaudi Arabia; Biomaterials DepartmentFaculty of Oral and Dental MedicineCairo UniversityEgypt; Department of Operative DentistryFaculty of Oral and Dental MedicineMisr International UniversityCairoEgypt; Dental Biomaterials DivisionFaculty of DentistryUmm AlQura UniversityMekkahSaudi Arabia; Department of Dental MaterialsFaculty of DentistryOctober University for Modern Sciences and Arts (MSA)Egypt; Department of OrthodonticsFaculty of DentistryKing Abdulaziz UniversityJeddahSaudi Arabia; Department of Cariology and Operative DentistryGraduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyoJapan; R&D AdhesivesIvoclar Vivadent AGSchaanFL9494Liechtenstein; Department of Oral BiologyGeorgia Regents UniversityCollege of Dental MedicineAugustaGAUnited States2020-01-092020-01-0920163005712https://doi.org/10.1016/j.jdent.2015.11.002PubMed ID : 26593780https://t.ly/kNN0mScopusObjectives The aim of the current study was to evaluate the effect of 2% CHX and 2% CHX-methacrylate compared to the resin dentin bonds created by a two-step etch-and-rinse adhesive system after 24h, 6min and 12min. Methods Microtensile bond strengths and interfacial nanoleakage within resindentin interfaces created by Adper Single Bond 2, with or without CHX or CHX-methacrylate pre-treatment for 30s on acid-etched dentin surfaces, were evaluated after 24h, 6min and 12min of storage in distilled water at 37C. Results Twelve months of storage resulted in a significant decrease in microtensile bond strength in the control group, and significant increases in silver nanoleakage. In contrast, Single Bond 2+CHX, and to a greater extent CHX-methacrylate, significantly reduced the rate of deterioration of resindentin interfaces over the 12min water storage period, in terms of bond strength. Conclusions Similar to Single Bond 2+CHX, Single Bond+CHX-methacrylates reduced the degradation of resin-bonded interfaces over a 12 month storage period. Thus it can be concluded that Single Bond 2+CHX-methacrylate may be important to improve durability of bonded interfaces and therefore, prolong the life span of adhesive restorations. Clinical significance Although CHX primers have been shown to enhance the durability of etch-and-rinse adhesives, that protection is lost after 2h. The use of CHX-methacrylate should last much longer since it may copolymerize with adhesive monomers, unlike CHX. 2015 Elsevier LtdEnglishOctober University for Modern Sciences and ArtsUniversity for Modern Sciences and ArtsMSA Universityجامعة أكتوبر للعلوم الحديثة والآدابBond strengthChlorhexidine digluconateChlorhexidine-methacrylateDentinNanoleakagebisphenol A bis(2 hydroxypropyl) ether dimethacrylatechlorhexidinechlorhexidine gluconatedental materialdentin bonding agentmethacrylic acid derivativeresinresin cementsingle bondtooth cementtopical antiinfective agentanalogs and derivativeschemistrydental acid etchingdental bondingdental proceduredentindrug effectshumanmolar toothproceduressurface propertytooth diseaseAcid Etching, DentalAnti-Infective Agents, LocalBisphenol A-Glycidyl MethacrylateChlorhexidineDental BondingDental CementsDental LeakageDental MaterialsDental Stress AnalysisDentinDentin-Bonding AgentsHumansMethacrylatesMolar, ThirdResins, SyntheticSurface PropertiesArticlehttps://doi.org/10.1016/j.jdent.2015.11.002PubMed ID : 26593780