El Hawary S.S.Zaghloul S.S.El Halawany A.M.El Bishbishy M.H.Department of PharmacognosyFaculty of PharmacyCairo UniversityCairo 11562Egypt; Department of PharmacognosyFaculty of PharmacyModern Sciences and Arts UniversityGizaEgypt; Faculty of PharmacyKing Abdulaziz UniversityJeddahSaudi Arabia2020-01-092020-01-0920131096620Xhttps://doi.org/10.1089/jmf.2013.2814PubMed ID 24180553https://t.ly/dONJDScopusThe volatile oils obtained from the leaves of four pecan cultivars growing in Egypt were evaluated for their chemical composition and antimicrobial activity. The selected cultivars (cv.) were Carya illinoinensis (Wangneh.) K. Koch. cv. Wichita, C. illinoinensis cv. Western Schley, C. illinoinensis cv. Cherokee, and C. illinoinensis cv. Sioux. The gas chromatography-mass spectrometry analyses revealed that the volatile oils from samples of the different cultivars differ in composition and percentage of their components. ?-Curcumene was found as the major constituent of the cv. Wichita oil, whereas germacrene D was the major component of cv. Sioux, cv. Cherokee, and cv. Western Schley. The antimicrobial activity was assayed using the Kirby-Bauer Method by measuring the zone of inhibition of growth. All volatile oils displayed an antimicrobial activity against the tested bacterial strains. On the other hand, only the volatile oil of cv. Wichita showed an antifungal effect on Aspergillus flavus. This work has identified candidates of volatile oils for future in vivo studies to develop antibiotic substitutes for the diminution of human and animal pathogenic bacteria. Nevertheless, the variations of the volatile oil components and antimicrobial potencies of the different studied cultivars, necessitate identifying the cultivars used in future studies. � 2013 Mary Ann Liebert, Inc., and Korean Society of Food Science and Nutrition.EnglishOctober University for Modern Sciences and Artsجامعة أكتوبر للعلوم الحديثة والآدابUniversity of Modern Sciences and ArtsMSA University?-curcumene8Carya illinoinensisAnti-bacterialAnti-fungalGermacrene Dalpha acoradienealpha ylangeneamphotericin Bantibiotic agentaromandrenebeta acoradienebeta curcumenebeta farnesenebeta pinenebourbonenecedrenecineolecopaenedelta cadineneessential oilgamma bisabolenegamma gurjunenegamma muurolenegermacrene Dguaiollimonenelongifolenepinenesalicylic acid methyl esterterpene derivativeterpenoidterpenoid derivativetetracyclineunclassified drugunindexed drugviridiflorolanimal experimentantibacterial activityantifungal activityantimicrobial activityarticleAspergillus flavusBacillus subtilisbacterial strainCandida albicanschemical analysischemical compositioncontrolled studycultivardisk diffusiondrug determinationdrug potencydrug screeningEgyptEnterococcus faecalisEscherichia colifungal straingenotypegrowth inhibitionhydrodistillationin vivo studymass fragmentographyNeisseria gonorrhoeaenonhumanpecanplant growthplant leafpriority journalPseudomonas aeruginosaStaphylococcus aureusAnimalsAnti-Bacterial AgentsAntifungal AgentsAspergillusBacteriaCaryaEgyptGas Chromatography-Mass SpectrometryHumansMicrobial Sensitivity TestsOils, VolatilePlant LeavesSesquiterpenes, GermacraneSpecies SpecificityArticlehttps://doi.org/10.1089/jmf.2013.2814PubMed ID 24180553