Abdulla, Nada MohamedMohamed, MonaAbdel Mohsen, Mohamed Mahmoud2022-12-272022-12-272022-112812 - 4944http://repository.msa.edu.eg/xmlui/handle/123456789/5303Background: Dental caries is a widespread, noncommunicable disease affecting half of world’s population. Thus, prevention rather than mere treatment of dental caries has become a decisive goal in dentistry. Therefor the adequacy of laser (Erbium, chromium-doped yttrium, scandium, gallium and garnet) irradiation and remineralizing agent were tested on artificially demineralized enamel. Methodology: Twenty human molars were selected, scaled, polished and sectioned into two equal buccal and lingual sections (n=40). Surfaces were coated with acid resistance nail varnish except for enamel window of 4x4 mm. The specimens were embedded in demineralizing solution for 3 days. They were randomly divided into two groups (n=20) according to type of remineralizing agent, group (MI): MI paste plus and group (RE): Remin Pro. They were applied according to manufacturer’s instructions. The groups were then divided into two subgroups (n=10); groups (MIL) and (REL). In both groups specimens were treated first with Er, Cr: YSGG Laser then remineralizing agents were applied. The weight % of Calcium and Phosphate were measured using EDX. The measurements were done before any treatment (control group), after demineralization and after remineralization. Representative specimens were selected for scanning. Results: The results of the study showed that (MI, RE and MIL) weren’t able to restore the minerals compared to the control group. While REL group was the only group similar to the control group. In addition, the intergroup comparison showed that REL had the highest remineralization compared to other groups. Conclusions: The combined use of laser and remineralizing agents improved enamel remineralizationen-USDental cariesRemineralizationRemin Pro;MI Paste Plus(Er,Cr:YSGG) Laser.Article