Yussif N.M.El-Mahdi F.M.Wagih R.Periodontology DepartmentFaculty of DentistryOctober University of Modern Sciences and Art (MSA)GizaEgypt; Medicine and Periodontology Dept. Faculty of DentistrySabha UniversityOral-DiagnosisEgypt; Medicine and Periodontology Dept.Faculty of Oral Dental MedicineCairo UniversityOral-DiagnosisEgypt2020-01-092020-01-09201717248914https://doi.org/10.11138/ccmbm/2017.14.3.312PubMed ID :https://t.ly/rxxqXScopusObjective. The purpose of this report is to investigate the role and efficiency of the intra-ligamentary injection of Vitamin D and calcium in the treatment of chronic periodontitis associated with hypothyroidism. Design. A 43-year-old female with suspected hypothyroidism who revealed severe chronic periodontitis with grade III mobility. Pre-operative periodontal and systemic control preceded the used intervention. After 3 months, intra-ligamentary injectable Vitamin D with calcium was introduced. Results. Clinical evaluation revealed great improvement of the injected sites. Marked reduction of mobility, pocket depth and bleeding were detected. Conclusions. Injectabe Vitamin D is an adjunctive treatment modality that needs to be discovered in another way. It may provide further solutions for the periodontal regeneration problem. Clinical studies with large sample sizes and long term follow up are needed.EnglishOctober University for Modern Sciences and Artsجامعة أكتوبر للعلوم الحديثة والآدابUniversity of Modern Sciences and ArtsMSA UniversityHypothyroidismIntraligamental injectionPeriodontitisVitamin Dantinuclear antibodyC reactive proteincal dcalciumchlorhexidinecyclic citrullinated peptide antibodyglycosylated hemoglobinthyrotropinuric acidvitamin Dabdominal distensionadultalbuminuriaanisocytosisarthralgiablood analysisbody weight gaincase reportchronic periodontitisclinical articledisease associationdry skinechocardiographyerythrocyte disordererythrocyte sedimentation rateface edemafemalefollow uphemoglobin blood levelhormone determinationhot flushhumanhypertensionhypothyroidisminsomniamedical historymenstruation disordermotor dysfunctionnormochromic normocytic anemiaperiodontal procedurephysical examinationprescriptionrashReviewrisk factortachycardiathyrotropin blood leveltooth diseasetooth extractiontooth radiographytreatment responseuric acid blood levelvitamin D deficiencyHypothyrodism as a risk factor of periodontitis and its relation with Vitamin D deficiency: Mini-review of literature and a case reportReviewhttps://doi.org/10.11138/ccmbm/2017.14.3.312PubMed ID :