Faculty Of Biotechnology Graduation Project 2018 - 2019

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Antioxidant, antimicrobial and anticancer effect of African rose
(October University for Modern Sciences and Arts, 2019) Abdelrahman Kamel, Teba
Origin of African rose (plum) was reported for the first time in china 470 B.C. these was the first written document about plum. African rose have shown to have lots of medical uses and also have the ability to prevent diseases related to food, also in promoting of health. Moreover, African rose have been considered as a therapeutic treatment for pathologies that are associated with inflammation and oxidative stress. It was reveal that African rose phenolic compounds have so many of biological activities such as anti-inflammatory, anticancer, antioxidant and antimicrobial activities. The recent study is to analysis in vitro antimicrobial, anticancer and antioxidant activities of phenols, tannins, flavonoids and alkaloids that were extracted from African rose. These extractions were used to extract phenolic compounds from African rose this is done by ethanolic extraction method. Then to determine the phytochemicals HPLC analysis was used, DPPH was used to evaluate antioxidant activity, to determine antimicrobial activity agar discs diffusion method was used. There were three different cancer cell lines that had been taken from human there are Liver cell line (HepG2), Brest cancer cell line (MCF-7) and colon cancer cell line (Caco-2) colon cancer these to determine cytotoxic activity beside using of neutral red (NR) assay.