Browsing by Author "Tijjani, Habibu"

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Health Benefits of Isoflavones Found Exclusively of Plants of the Fabaceae Family
(Springer, 8/25/2020) Suddhasuchi, Das; Sharangi, A. B.; Egbuna, Chukwuebuka; Jeevanandam, Jaison; Ezzat, Shahira M; Adetunji, Charles Oluwaseun; Tijjani, Habibu; Olisah, Michael Chinedu; Patrick-Iwuanyanwu, Kingsley C.; Adetunji, Juliana Bunmi; Ifemeje, Jonathan C.; Akram, Muhammad; Moboladji, Bankole Marc; Onyeike, Precious Chidinma
This chapter presents recent studies on the health benefits of isoflavones from the flowering plants of the Leguminosae family- Fabaceae, which are commonly known as the legume, pea, or bean family. Notable agricultural and food plants in this family are Glycine max (soybean), Phaseolus (beans), Pisum sativum (pea), Medicago sativa (alfalfa), Arachis hypogaea (peanut), Ceratonia siliqua (carob), and Glycyrrhiza glabra (liquorice). It was established from literary sources that extracts from these plants, including the invasive species contains important isoflavones. Prominent among the isoflavones biologically active aglycones: genistein, daidzein, and glycitein. Other isoflavones are ononin and sissotrin, with their aglycones, formononetin and biochanin A respectively. These compounds have been described to be active against some life-threatening diseases such as cancer, diabetes, cardiovascular diseases among others.
Health Benefits of Isoflavones Found Exclusively of Plants of the Fabaceae Family
(Springer, 8/25/2020) Das, Suddhasuchi; Sharangi, A. B; Egbuna, Chukwuebuka; Jeevanandam, Jaison; Ezzat, Shahira M; Adetunji, Charles Oluwaseun; Tijjani, Habibu; Olisah, Michael Chinedu; Patrick-Iwuanyanwu, Kingsley C; Adetunji, Juliana Bunmi; Ifemeje, Jonathan C; Akram, Muhammad; Moboladji, Bankole Marc; Onyeike, Precious Chidinma
This chapter presents recent studies on the health benefits of isoflavones from the flowering plants of the Leguminosae family- Fabaceae, which are commonly known as the legume, pea, or bean family. Notable agricultural and food plants in this family are Glycine max (soybean), Phaseolus (beans), Pisum sativum (pea), Medicago sativa (alfalfa), Arachis hypogaea (peanut), Ceratonia siliqua (carob), and Glycyrrhiza glabra (liquorice). It was established from literary sources that extracts from these plants, including the invasive species contains important isoflavones. Prominent among the isoflavones biologically active aglycones: genistein, daidzein, and glycitein. Other isoflavones are ononin and sissotrin, with their aglycones, formononetin and biochanin A respectively. These compounds have been described to be active against some life-threatening diseases such as cancer, diabetes, cardiovascular diseases among others.
Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology
(Hindawi, 7/30/2021) Egbuna, Chukwuebuka; Parmar, Vijaykumar K.; Jeevanandam, Jaison; Ezzat, Shahira M; Patrick-Iwuanyanwu, Kingsley C; Adetunji, Charles Oluwaseun; Khan, Johra; Onyeike, Eugene N; Uche, Chukwuemelie Zedech; Akram, Muhammad; Ibrahim, Mervat S; El Mahdy, Nihal M; Awuchi, Chinaza Godswill; Saravanan, Kaliyaperumal; Tijjani, Habibu; Odoh, Uchenna Estella; Messaoudi, Mohammed; Ifemeje, Jonathan C; Olisah, Michael C; Ezeofor, Nebechi Jane; Chikwendu, Chukwudi Jude; Ibeabuchi, Chinwe Gloria
Nanoparticles are of great importance in development and research because of their application in industries and biomedicine. )e development of nanoparticles requires proper knowledge of their fabrication, interaction, release, distribution, target, compatibility, and functions. )is review presents a comprehensive update on nanoparticles’ toxic effects, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. Recent studies have found that nanoparticles may cause serious health effects when exposed to the body through ingestion, inhalation, and skin contact without caution. )e extent to which toxicity is induced depends on some properties, including the nature and size of the nanoparticle, the surface area, shape, aspect ratio, surface coating, crystallinity, dissolution, and agglomeration. In all, the general mechanisms by which it causes toxicity lie on its capability to initiate the formation of reactive species, cytotoxicity, genotoxicity, and neurotoxicity, among others.