Browsing by Author "Shehata M."
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Item C(-260)T polymorphism in CD14 receptor gene of Egyptians with acute myocardial infarction(Bentham Science Publishers B.V., 2018) Hashad I.M.; Hossni N.M.; Abdel Rahman M.F.; Shehata M.; Shaban G.; Gad M.Z.; Clinical Biochemistry Unit; Faculty of Pharmacy and Biotechnology; The German University in Cairo; Cairo; Egypt; Biochemistry Department; Faculty of Pharmacy; October University for Modern Sciences and Arts (MSA); Cairo; Egypt; Department of Cardiology; Faculty of Medicine; Ain Shams University; Cairo; Egypt; Department of Cardiology; National Heart Institute; Cairo; EgyptBackground: Despite the significance of the traditional risk factors, recently published studies have suggested that inflammatory processes and variations in the genetics of the inflammatory system may participate in the initiation of atherosclerosis and its complications. Objective: To investigate the possible association between CD14 C(-260)T (rs2569190) gene polymorphism and the risk of acute myocardial infarction in the Egyptian population. Methods: We enrolled 100 acute myocardial infarction patients in addition to 107 healthy controls. Deoxyribonucleic acid was extracted, purified and used for the genotype assay of C(-260)T polymorphism in promoter region of CD14 gene. Genotyping was conducted using polymerase chain reaction-restriction fragment length polymorphism. Polymerase chain reaction product was digested using a restriction enzyme and the digestion products were specified. Serum CD14 levels were determined by Enzyme Linked Immunosorbent Assay. Results: CD14 genotypic distribution (CC: 15.9% vs. 16%, CT: 62.6% vs. 58%, TT: 21.5% vs. 26% in controls versus acute myocardial infarction patients, p > 0.05 for all variables) and allele frequencies (C allele: 47% vs., 45%, T allele: 52% vs. 55% in controls versus acute myocardial infarction patients, p > 0.05 for all variables) did not show a statistical significant difference. Serum CD14 levels were elevated in acute myocardial infarction patients (5.73�0.62 vs. 4.48�0.28 pg/ml, p < 0.05). However, there was no statistically significant difference in serum CD14 levels among different CD14 genotypes. Conclusion: CD14 C-(260)T polymorphism is not associated with incidence of acute myocardial infarction in Egyptians who showed elevated serum CD14 levels in comparison to healthy individuals. � 2018 Bentham Science Publishers.Item Performance Evaluation of RZF Precoding in Multi-User MIMO Systems(Institute of Electrical and Electronics Engineers Inc., 2019) Saleeb B.; Shehata M.; Mostafa H.; Fahmy Y.; Electronics and Communications Engineering Department; MSA University; Giza; 15525; Egypt; Electronics and Communication Engineering Department; Cairo University; Giza; 12613; Egypt; Center for Nano-electronics and Devices Zewail City for Science and Technology; Giza; 12588; EgyptIn this paper, the transmission performance of the downlink of linearly precodied multi-user multiple input-multiple output (MIMO) systems is investigated. The zero forcing (ZF), regularized ZF (RZF) and minimum mean squared error (MMSE) precoding schemes are considered, and the bit error rate (BER) is adopted as the performance metric of interest. Simulation results indicate that, an adequate BER performance is achieved by the proper control of the design parameters of RZF precoding. Moreover, a relationship between the number of users' antennas and the BS is observed, such that an adequate BER performance is achieved. 2019 IEEE.