Browsing by Author "Rostom, Yasmin"

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Advanced Approaches in Green Univariate Spectrophotometric Methods
(wiley, 2024-01) Lotfy, Hayam M; Saleh, Sarah S; Rostom, Yasmin; Obaydo, Reem H; Ahmed, Dina A
The pharmaceutical industry and market have shown a tremendous evolution where different new pharmaceuticals and pharmaceutical combinations have been introduced in order to increase patient compliance and obtain the required outcomes. On the other hand, this evolution has raised a challenge in the field of drug analysis, where new applicable methods of analysis needed to be developed and validated to ensure that the right doses would reach patients free from any undesired compounds such as impurities, adulterants, or interfering substances that might lead to any undesirable side effects. This chapter highlights the advanced approaches in green univariate spectrophotometric methods based on basic mathematical techniques, such as subtraction, division, and multiplication, for assaying the components of multicomponent mixtures in their different pharmaceutical dosage forms utilising inexpensive, affordable, and eco-friendly facilities.
Guidelines for Accurate Application of Green and White Analytical Concepts: Merits Vs Demerits with Insights of Significant Milestones of Assessment Tools Applied for Antiviral Drugs
(Elsevier Inc, 2024-01) Saleh, Sarah S; Obaydo, Reem H; El Hamd, Mohamed A; Rostom, Yasmin; Mohamed, Dalia; Lotfy, Hayam M
In recent years, there has been a growing focus in analytical research on the ecological and sustainable aspects of analytical methodologies. However, it is necessary to apply the relevant metrics to evaluate the effectiveness of certain analytical methods. The present study aims to conduct a thorough analysis of the major turning points, merits, and demerits of some reported methods carried out to determine anti-viral drugs. Since the COVID-19 pandemic in 2020, researchers have become interested in antiviral drugs because it was the class of interest for facing the challenges of this pandemic. That’s why, a comprehensive application of several relevant green metrics has been reviewed. Additionally, the study intends to choose tools that have been reported as being green to use, explain the data that has been gathered, compare the data to one another, and highlight the benefits of particular features in each tool based on the timeline progress of using these tools. In addition, suggestions were made for adapting each tool to the recommended guidelines. Case studies were presented to highlight the proper application of each assessment tool.
Guidelines for accurate application of green and white analytical concepts: Merits Versus demerits with insights of significant milestones of assessment tools applied for antiviral drugs
(Elsevier Inc, 2024-01) Saleh, Sarah S; Obaydo, Reem H; El Hamd, Mohamed A; Rostom, Yasmin; Mohamed, Dalia; Lotfy, Hayam M
In recent years, there has been a growing focus in analytical research on the ecological and sustainable aspects of analytical methodologies. However, it is necessary to apply the relevant metrics to evaluate the effectiveness of certain analytical methods. The present study aims to conduct a thorough analysis of the major turning points, merits, and demerits of some reported methods carried out to determine anti-viral drugs. Since the COVID-19 pandemic in 2020, researchers have become interested in antiviral drugs because it was the class of interest for facing the challenges of this pandemic. That’s why, a comprehensive application of several relevant green metrics has been reviewed. Additionally, the study intends to choose tools that have been reported as being green to use, explain the data that has been gathered, compare the data to one another, and highlight the benefits of particular features in each tool based on the timeline progress of using these tools. In addition, suggestions were made for adapting each tool to the recommended guidelines. Case studies were presented to highlight the proper application of each assessment tool.