Browsing by Author "Ahmed, Alaa"
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Item Desert date seed extract‑loaded chitosan nanoparticles ameliorate hyperglycemia and insulin defciency through the reduction in oxidative stress and infammation(Nature Publishing Group, 2024-03) Farid, Alyaa; Ahmed, Alaa; Alaa, Olaya; Safwat, GehanPlants represents a huge source of bioactive materials that have been used since the old times in the treatment of many diseases. Balanites aegyptiaca, known as desert date, has been used in treatment of fever, diabetes and bacterial infection. Desert dates contains a hard seed that resembles 50–60% of the fruit. The seed extract contains many fatty acids, amino acids and other bioactive materials that gives the extract its antioxidant and anti-infammatory properties. The study aimed to use Balanites seed extract-loaded chitosan nanoparticles (SeEx-C NPs) for the treatment of streptozotocin (STZ)induced diabetes in male Sprague Dawley rats. Animals were divided into two main divisions (healthy and diabetic rats). Each division contained seven groups (5 rats/group): control untreated group I, SeEx treated group II and group III (10 and 20 mg/kg b.w., respectively), C NPs treated group IV and group V (10 and 20 mg/kg b.w., respectively) and SeEx-C NPs treated group VI and group VII (10 and 20 mg/kg b.w., respectively). The therapeutical efects of SeEx-C NPs were evaluated through biochemical and immunological assessments in rats’ pancreases. The results showed that SeEx-C NPs (10 and 20 mg/kg b.w.) reduced the oxidative stress and infammation in rats’ pancreases allowing the islets neogenesis. The loading of SeEx on C NPs allowed the delivery of fatty acids (oleic, lauric and myristic acid), amino acids (lysine, leucine, phenylalanine and valine) and minerals to pancreatic beta-cells in a sustainable manner. SeEx-C NPs administration successfully increased insulin secretion, allowed pancreatic islets neogenesis and reduced oxidative stress and infammation.Item The effects of celebrity endorsement on consumer’s purchase intentions in the sportswear industry applied on (Nike)(MSA UNIVERSITY, 2021) Moussa, Ahmed; Ahmed, Alaa; Sherif, MaryamPurpose: The purpose of this paper is to investigate factors affecting the consumer’s purchase intentions, mentioning the relationship between celebrity endorsement variables affecting consumer purchase intentions. Conceptually, this research will contribute to the advertisements endorsed by celebrities targeting the message to marketers to best know the variables that affect consumer’s purchase intentions positively before introducing an advertisement. Empirically, the research studies Tv and social media endorsed advertisements. Methodology: Researchers successfully utilized a combination of primary and secondary data through the conduction of in-depth interviews with a convenient sample by using previous researcher’s literatures to measure the relationship between the variables assessing results of a questionnaire. Online questionnaires were collected from 210 persons who are aware of the advertisement using IBM’s statistical package for the social sciences (SPSS). Findings: Researchers' findings assured the positive relationship between the celebrity endorsement characteristics such as the physical attractiveness and celebrity credibility, the match-up of the celebrity endorsement and the product endorsed and its impact on the consumers purchase intentions. Implications: Finally, this research provides marketers and brands with practical implications about factors that should be taken into consideration when going for a product endorsement. Celebrity’s good physical attractiveness, celebrities’ high credibility or reputation, and match-up with a celebrity such as Cristiano Ronaldo were claimed to affect consumer’s purchase intentions applied on Nike Shoes. Also, the research investigates that these factors have an effect on consumer’s purchase intentions.