Faculty Of Pharmacy Research Paper

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    A critical analysis of extraction techniques used for botanicals: Trends, priorities, industrial uses and optimization strategies
    (2018) Belwal T.; Ezzat, Shahira M; Rastrelli L.; Bhatt I.D.; Daglia M.; Baldi A.; Devkota H.P.; Orhan I.E.; Patra J.K.; Das G.; Anandharamakrishnan C.; Gomez-Gomez L.; Nabavi S.F.; Nabavi S.M.; Atanasov A.G.; G. B. Pant National Institute of Himalayan Environment and Sustainable Development; Kosi-Katarmal; Almora; Uttarakhand 263643; India; Department of Pharmacognosy; Faculty of Pharmacy; Cairo University; Giza; Egypt; Department of Pharmacognosy; Faculty of Pharmacy; October University for Modern Science and Arts (MSA); 6th October; 12566; Egypt; Dipartimento diFarmacia; University of Salerno; via Giovanni Paolo II; Fisciano; 84084; Italy; Department of Drug Sciences; Medicinal Chemistry and Pharmaceutical Technology Section; Pavia University; VialeTaramelli 12; Pavia; 27100; Italy; School of Pharmacy; Kumamoto University; 5-1 Oe-honmachi; Chuo ku; Kumamoto 862-0973; Japan; Program for Leading Graduate Schools; Health life Science: Interdisciplinary and Glocal Oriented (HIGO) Program; Kumamoto University; Kumamoto; Japan; Department of Pharmacognosy; Faculty of Pharmacy; Gazi University; Ankara; 06330; Turkey; Research Institute of Biotechnology & Medical Converged Science; Dongguk University-Seoul; Goyang-si; 10326; South Korea; Computational Modelling and Nanoscale Processing Unit; Indian Institute of Food Processing Technology; Thanjavur; Tamil Nadu 613005; India; Facultad de Farmacia; Universidad de Dastilla-La Mancha; Campus Universitario S/n; Albacete; 02071; Spain; Applied Biotechnology Research Center; Baqiyatallah University of Medical SciencesTehran; Iran; Molecular Biology Department; Institute of Genetics and Animal Breeding of the Polish Academy of Sciences; Jastrzebiec; Poland; Department of Pharmacognosy; University of Vienna; Althanstrasse14; Vienna; 1090; Austria
    Plant extracts have been long used by the traditional healers for providing health benefits and are nowadays suitable ingredient for the production of formulated health products and nutraceuticals. Traditional methods of extraction such as maceration, percolation, digestion, and preparation of decoctions and infusions are now been replaced by advanced extraction methods for increased extraction efficiency and selectivity of bioactive compounds to meet up the increasing market demand. Advanced techniques use different ways for extraction such as microwaves, ultrasound waves, supercritical fluids, enzymes, pressurized liquids, electric field, etc. These innovative extraction techniques, afford final extracts selectively rich in compounds of interest without formation of artifacts, and are often simple, fast, environment friendly and fully automated compared to existing extraction method. The present review is focused on the recent trends on the extraction of different bioactive chemical constituents depending on the nature of sample matrices and their chemical classes including anthocyanins, flavonoids, polyphenols, alkaloids, oils, etc. In addition, we review the strategies for designing extraction, selection of most suitable extraction methods, and trends of extraction methods for botanicals. Recent progress on the research based on these advanced methods of extractions and their industrial importance are also discussed in detail. � 2017 Elsevier B.V.