Protective effect of Allium atroviolaceum-synthesized SeNPs on aluminum-induced brain damage in mice

Othman, Mohamed S; Obeidat, Sofian T; Aleid, Ghada M; Al-Bagawi, Amal H; Fehaid, Alaa; Habotta, Ola A; Badawy, Mohamed M; Elganzoury, Sara S; Abdalla, Mohga S; Abdelfattah, Mohamed S; Daiam, Mohamed A; Abdel Moneim, Ahmed E

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Protective effect of Allium atroviolaceum-synthesized SeNPs on aluminum-induced brain damage in mice

Othman, Mohamed S; Obeidat, Sofian T; Aleid, Ghada M; Al-Bagawi, Amal H; Fehaid, Alaa; Habotta, Ola A; Badawy, Mohamed M; Elganzoury, Sara S; Abdalla, Mohga S; Abdelfattah, Mohamed S; Daiam, Mohamed A; Abdel Moneim, Ahmed E

Full Text link: http://repository.msa.edu.eg/xmlui/handle/123456789/5265

Date issued: 2022-11

Scientific Journal Rankings: Click Here

Doi: https://doi.org/10.1515/chem-2022-0245

Publisher: Walter de Gruyter GmbH

Series Info: Open Chemistry;20(1):1365-1377

Type: Article

Keywords: aluminum , Allium atroviolaceum , selenium nanoparticles , oxidative stress , apoptosis , acetylcholinesterase , BDNF

Abstract:

reduction in AChE as compared with the AlCl3 group. Therefore, our results indicate that SeNPs-AaE has a potential neuroprotective effect against Al-mediated neurotoxic effects because of its powerful antioxidant, anti-inflammatory, anti-apoptotic, and neuromodulatory activities.

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