El-Naggar A.M.; Abou-El-Regal M.M.; El-Metwally S.A.; Sherbiny F.F.; Eissa I.H.
(Springer International Publishing, 2017)
Thymidylate synthase (TS), one of folate-dependent enzymes, is a key and well-recognized target for anticancer agents. In this study, a series of 6-aryl-5-cyano thiouracil derivatives were designed and synthesized in ...