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Browsing Faculty Of Pharmacy Research Paper by Title

Now showing items 260-279 of 1119

Dapagliflozin modulates neuronal injury via instigation of LKB1/p-AMPK/GABAB R2 signaling pathway and suppression of the inflammatory cascade in an essential tremor rat model

Kamel, Ahmed S; Farrag, Sama M; Mansour, Heba M; Nassar, Noha N; Saad, Muhammed A (Taylor and Francis Ltd., 2023-04)

Background Although, disturbances in cellular energy demarcate the neuronal hyperexcitability in essential tremor (ET), nevertheless, no available data relates energy sensors and GABAergic neurotransmission in ET. Noteworthy, ...
Dapson in Heterocyclic Chemistry, Part V: Synthesis, Molecular Docking and Anticancer Activity of Some Novel Sulfonylbiscompounds Carrying Biologically Active Dihydropyridine, Dihydroisoquinoline, 1,3-Dithiolan, 1,3-Dithian, Acrylamide, Pyrazole, Pyrazolopyrimidine and Benzochromenemoieties

Mohammed Ghorab, Mostafa; Sulaiman Al-Said, Mansour; Mohammed Nissan, Yassin (Chemical and Pharmaceutical Bulletin, 2012)

N,N′-(4,4′-Sulfonylbis(4,1-phenylene))bis(2-cyanoacetamid) 2 was utilized as a key intermediate for the synthesis of novel dihydropyridines 3, 4, 8, dihydroisoquinolines 5–7, dithiolan 10, dithian 11, acrylamide ...
Dapson in heterocyclic chemistry, part VIII: synthesis, molecular docking and anticancer activity of some novel sulfonylbiscompounds carrying biologically active 1,3-dihydropyridine, chromene and chromenopyridine moieties

Al-Said, Mansour S; Ghorab, Mostafa M; Nissan, Yassin M (Springer Link, 2012-07)

[HTML] من springer.com Dapson in heterocyclic chemistry, part VIII: synthesis, molecular docking and anticancer activity of some novel sulfonylbiscompounds carrying biologically active 1, 3 … المؤلفون Mansour S Al-Said, ...
Dasatinib ameliorates thioacetamide-induced liver fibrosis: modulation of miR-378 and miR-17 and their linked Wnt/b-catenin and TGF-b/smads pathways

Zaafan, Mai A; Abdelhamid, Amr M (Taylor and Francis, 11/12/2021)

Hepatic stellate cells activation (HSCs) plays a crucial role in the pathogenesis of liver fibrosis. Specific microRNAs have been suggested to affect the activation of HSCs via various signalling pathways including TGF-b/smads ...
Date Supplement and Iron Salts Plus Physical Activity on Efficiency of Iron Absorption

Hassanin, Soha Osama; Atris, Saleh A; Mustafa, Mohie El Deen M; Nadir, A. S (INT JOURNAL PHARMACEUTICAL RESEARCH & ALLIED SCIENCES, 2019)

The aim of this study was to investigate the effect of date supplement and iron plus physical activity on anemic female students. This study includes 40 anemic female students, from the new valley university; they were ...
Delineating a potent antiviral activity of Cuphea ignea extract loaded nano-formulation against SARS-CoV-2: In silico and in vitro studies

Mahmoud, Dina B; Ismail, Walaa M; Moatasim, Yassmin; Kutkat, Omnia; ElMeshad, Aliaa N; Ezzat, Shahira M; El Deeb, Kadriya S; El-Fishawy, Ahlam M; Gomaa, Mokhtar R; Kandeil, Ahmed; Al-karmalawy, Ahmed A; Ali, Mohamed A; Mostafa, Ahmed (Elsevier, 9/15/2021)

Journal of Drug Delivery Science and Technology Available online 15 September 2021, 102845 In Press, Journal Pre-proofWhat are Journal Pre-proof articles? Delineating a potent antiviral activity of Cuphea ignea extract ...
Densitometric and Ratio Spectra Methods for Simultaneous Determination of Sulfaquinoxaline Sodium and Pyrimethamine in Binary Mixture

El Sanabary, Hoda F.; Fouad, Manal M.; El Demerdash, Asmaa O; Abdel Razeq, Sawsan A. (CAIRO UNIVERSITY, 1/16/2019)

Four methods were developed for simultaneous determination of sulfaquinoxaline-Na and pyrimethamine in their combined pharmaceutical formulations. The first one was a densitometric method where chloroform-methanol (9: 1, ...
Densitometric and UV-Spectrophotometric Methods for Simultaneous Determination of Spiramycin adipate in Binary Mixture with Oxytetracycline-HCl or Tetracycline-HCl

El Sanabary, Hoda F; Fouad, Manal M; Abdel Razeq, Sawsan A.; El Demerdash, Asmaa O. (NLM, 2018)

Five methods were developed for simultaneous determination of spiramycin adipate and oxytetracycline-HCl and/or tetracycline-HCl in their pharmaceutical formulations. The first one was a densitometric evaluation of thin-layer ...
Dereplication Analysis and Antitrypanosomal Potential of the Red Sea Sponge Amphimedon sp. Supported by Molecular Modelling

Hisham Shady, Nourhan; Elfakharany, Zeinab; Salem, M. Alaraby; Ahmed, Safwat; Fouad, Mostafa A.; Salah Kamel, Mohamed; Krischke, Markus; Mueller, Martin J.; Abdelmohsen, Usama Ramadan (Springer, 2020-03)

The present investigation was oriented to the discovery of chemical compounds from the Red Sea sponge Amphimedon sp., as a source of active agents against Trypanosoma brucei, the causal agent of human sleeping sickness. ...
Derivative constant wavelength synchronous fluorescence spectrometry for the simultaneous detection of cefadrine and cefadroxil in water samples

Elbalkiny H.T.; Yehia A.M.; Riad S.M.; Elsaharty Y.S. (Elsevier B.V., 2020)

A sensitive accurate spectrofluorimetric technique was developed to detect cefadroxil and cefradine traces in water samples simultaneously, by applying a procedure based on the formation of hydrolysis products corresponding ...
Dermatological Manifestations Associated with Covid-19 Patients in Elbagour General Hospital, El-Menoufia Governorate

Farag, Azza Gaber Antar; labeeb, Azza Zagloul; Amin, Marwa Abo El-Nour Gamal; Elshaib, Mustafa Elsayed; Elnaidany, Nada Farag (Ain Shams University Faculty of Medicine, 2022-05)

Background: Corona virus-19 disease (COVID-19) marked the beginning of a new pandemic COVID-19 after massive numbers of acute pneumonia with unknown origin. Some COVID-19 confirmed patients experienced some skin lesions ...
Design and Assessment of Chlorpheniramine Maleate Sublingual Tablets Using Novel Ternary Phase Superdisintegrants

M. Elbakry, Asmaa; H. Elosaily, Ghada; E. Yassin, Ghada; A. Zaky, Alaa (Journal of American Science, 2014)

Sublingual tablets are gaining popularity over conventional tablets due to their convenience in administration and suitability for elderly and children who have swallowing difficulties. The aim of this study was to formulate ...
Design and evaluation of fast dissolving oro-dispersible films of metoclopramide hydrochloride using 32 multifactorial designs

Yassin G.E.; Abass H.A. (Innovare Academics Sciences Pvt. Ltd, 2016)

Objective: The objective of the present work was to develop and optimize fast dissolving orodispersible films containing metoclopramide hydrochloride using 32 multifactorial designs. Methods: The films were prepared by ...
Design and optimization of topical terbinafine hydrochloride nanosponges: Application of full factorial design, in vitro and in vivo evaluation

Amer, R; El-Osaily, G; Gad, S (Wolters Kluwer Medknow Publications, 2020-03)

Terbinafine hydrochloride (THCl) has a broad-spectrum antifungal activity. THCl has oral bioavailability 40%, which increases dosing frequency of the drug, thus leads to some systemic side effects. Sustained release THCl ...
Design and synthesis of new quinoxaline derivatives as anticancer agents and apoptotic inducers

El Newahie A.M.S.; Nissan Y.M.; Ismail N.S.M.; Abou El Ella D.A.; Khojah S.M.; Abouzid K.A.M. (MDPI AG, 2019)

The quinoxaline scaffold is a promising platform for the discovery of active chemotherapeutic agents. Three series of quinoxaline derivatives were synthesized and biologically evaluated against three tumor cell lines (HCT116 ...
Design and synthesis of novel antimicrobial acyclic and heterocyclic dyes and their precursors for dyeing and/or textile finishing based on 2-n-acylamino-4,5,6,7-tetrahydrobenzo[b]thiophene systems

Shams H.Z.; Mohareb R.M.; Helal M.H.; Mahmoud A.E.-S. (2011)

A series of novel polyfunctionalized acyclic and heterocyclic dye precursors and their respective azo (hydrazone) counterpart dyes and dye precursors based on conjugate enaminones and/or enaminonitrile moieties were ...
Design, optimization, and validation of thin-layer chromatography-densitometry and chemometry-assisted spectrophotometry: A comparative study applied on quaternary mixture

Salem H.; Hassan N.Y.; Lotfy H.M.; Saleh S.S. (Akademiai Kiado Rt., 2015)

This work presents a comparative study on the development and validation of two analytical techniques applied for the simultaneous determination of hydrocortisone acetate (HCA), fusidic acid (FSA), methyl paraben (MPB), ...
Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines

Aziz, Marian W; Kamal, Aliaa M; Mohamed, Khaled O; Elgendy, Adel A (Elsevier, 06/01/2021)

New acetamide (IV a-e) and 1,3-thiazolidinone derivatives (VII a-e) were designed, synthesized and assessed for their cytotoxic activity against MCF-7 and A549 cell lines along with their lead compounds (erlotinib and ...
Design, synthesis and biological evaluation of some novel sulfonamide derivatives as apoptosis inducers

Mohamed K.O.; Nissan Y.M.; El-Malah A.A.; Ahmed W.A.; Ibrahim D.M.; Sakr T.M.; Motaleb M.A. (Elsevier Masson SAS, 2017)

Several novel thiazolidinone and fused thiazolidinone derivatives bearing benzenesulfonamide moiety were synthesized and confirmed via spectral and elemental analyses. The newly synthesized compounds were evaluated for ...
Design, synthesis and cytotoxic activity of certain novel chalcone analogous compounds

El-Meligie S.; Taher A.T.; Kamal A.M.; Youssef A. (Elsevier Masson SAS, 2017)

A series of chalcone analogous compounds were designed and synthesized. Replacing/substituting the enone or ethylenic bridge of the parent chalcone with rigid heterocyclic moieties or substituted aromatic amines gave ...

Now showing items 260-279 of 1119

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